Evidence map›Paper›PMID 34675502›Full record

ArticleInternational journal of chronic obstructive pulmonary disease

Predictors of 30- and 90-Day COPD Exacerbation Readmission: A Prospective Cohort Study.

Jaber S Alqahtani, Yousef S Aldabayan, Abdulelah M Aldhahir, Ahmad M Al Rajeh, Swapna Mandal, John R Hurst

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06348966 (Predictors of Hospital Readmission for Chronic Obstructive Pulmonary Disease Patients,A Prospective Cohort Study), which is not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06348966 unknown statusnot on this map

Predictors of Hospital Readmission for Chronic Obstructive Pulmonary Disease Patients,A Prospective Cohort Study

TypeobservationalSponsorAssiut UniversityRan2024 to 2026Enrolled188ConditionsHospital Radmission for COPD Patients
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Respiratory Muscle Strength and Mortality in Patients with COPD: A Systematic Review and Meta-Analysis.International journal of chronic obstructive pulmonary disease · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Symptomatic Changes Associated With a Pharmacist-Led COPD Program.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026
    Article
  8. Article
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  12. Article
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  16. Real-World Evaluation of an EHR-Enabled Chronic Obstructive Pulmonary Disease Assessment Test.International journal of chronic obstructive pulmonary disease · 2025
    Observational
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jaber S AlqahtaniUCL Respiratory, University College London, London, UK.ORCID 0000-0003-1795-5092
Yousef S AldabayanRespiratory Care Department, College of Applied Medical Sciences, King Faisal University, Al-Hasa, Saudi Arabia.
Abdulelah M AldhahirRespiratory Care Department, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia.
Ahmad M Al RajehRespiratory Care Department, College of Applied Medical Sciences, King Faisal University, Al-Hasa, Saudi Arabia.ORCID 0000-0003-2559-416X
Swapna Mandal *UCL Respiratory, University College London, London, UK.
John R Hurst *UCL Respiratory, University College London, London, UK.ORCID 0000-0002-7246-6040
King Faisal University · SARoyal Free London NHS Foundation Trust · GBJazan University · SAPrince Sultan Military College of Health Sciences

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReadmission following COPD exacerbation is a common and challenging clinical problem. New approaches to predicting readmissions are required to help mitigate risk and develop novel interventions.

methodsWe conducted a prospective cohort study in 82 COPD patients admitted due to an exacerbation of COPD. Lung function measures [spirometry, forced oscillation technique (FOT) indices and peak inspiratory flow rate (PIFR)], inflammatory biomarkers and patient-reported outcomes including previous exacerbation history, breathlessness, quality of life and frailty were measured at admission and discharge. We prospectively followed patients for 30 and 90 days to identify predictors for readmission.

resultsThe readmission rate within 30 days was 38%, and 56% within 90 days. Previous exacerbations, higher COPD Assessment Test score at discharge, frailty, reduced PIFR and increased length of stay were significantly associated with 30-day readmission. PIFR at discharge and frailty had the highest predictive ability for 30-day readmission using area under receiver operating characteristic curves (AUC 0.86, 95% CI 0.78-0.95, p < 0.001 and AUC 0.81, 95% CI 0.71-0.90, p < 0.001, respectively). Ninety-day readmissions were significantly associated with previous exacerbations and hospitalisations, higher CAT score at discharge, frailty, depression, lower PIFR and greater expiratory flow limitation (EFL) in the supine position. The best predictive variable in multivariable analysis for both 30- and 90-day readmission was PIFR at discharge.

conclusionPIFR, CAT score, frailty, and EFL were found to be associated with 30- and 90-day readmission following COPD exacerbation. These findings help identify those at highest risk and to optimise care prior to discharge.

Indexed as

Pulmonary Disease, Chronic ObstructiveDisease ProgressionHumansPatient ReadmissionProspective StudiesQuality of LifeRisk FactorsSpirometryadmissionCOPDEFLexacerbationfrailtyPIFRpredictorreadmissionrisk factor

Identifiers

PMID34675502
PMCPMC8504869
OpenAlexW3203557682

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.