Evidence map›Paper›PMID 34675389›Full record

ArticleNature immunology2021

Immune-mediated inflammation across disease boundaries: breaking down research silos.

Christopher D Buckley, Lorna Chernajovsky, Yuti Chernajovsky, Louise K Modis, Luke A O'Neill, Doug Brown, Rachel Connor, David Coutts, Elizabeth A Waterman, Paul P Tak

Abstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Preclinical IBD: One more piece of the puzzle.United European gastroenterology journal · 2023
    Article
  9. Review
  10. Novel antiinflammatory biologics shaped by parasite-host coevolution.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christopher D BuckleyThe Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Lorna ChernajovskyThe Lorna and Yuti Chernajovsky Biomedical Research Foundation, Whitstable, UK.
Yuti ChernajovskyThe Lorna and Yuti Chernajovsky Biomedical Research Foundation, Whitstable, UK. yuti@chernajovskyfoundation.org.uk.ORCID http://orcid.org/0000-0002-3388-8259
Louise K ModisImmunology Research, GSK, Stevenage, UK.
Luke A O'NeillSchool of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0002-4333-2748
Doug BrownBritish Society for Immunology, London, UK.
Rachel ConnorJuvenile Diabetes Research Foundation, London, UK.
David CouttsMultiple Sclerosis Society, London, UK.ORCID http://orcid.org/0000-0003-0527-007X
Elizabeth A WatermanVersus Arthritis, Chesterfield, UK.
Paul P TakThe Lorna and Yuti Chernajovsky Biomedical Research Foundation, Whitstable, UK.

Funding

Medical Research Council MR/S025308/1Medical Research Council MR/S035850/1Wellcome Trust 109443/Z/15/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Allergy and ImmunologyBiomedical ResearchAnimalsAnti-Inflammatory AgentsDiffusion of InnovationDrug DiscoveryHumansImmune SystemImmunotherapyInflammationInflammation MediatorsMolecular Targeted TherapySignal TransductionAnti-Inflammatory AgentsInflammation Mediators

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.