ArticleScientific reports2021
An Emiliania huxleyi pan-transcriptome reveals basal strain specificity in gene expression patterns.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 11 citations in OpenAlex.
- Mapping the transcriptional landscape of algal resistance to viral infection reveals a core expression program.The New phytologist · 2025Article
- Single-cell RNA-seq of the rare virosphere reveals the native hosts of giant viruses in the marine environment.Nature microbiology · 2024Article
- The consequences of viral infection on protists.Communications biology · 2024Review
- Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics.Science advances · 2023Article
- Lipid biomarkers for algal resistance to viral infection in the ocean.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Homing in on the rare virosphere reveals the native host of giant viruses.bioRxiv : the preprint server for biology · 2023Article
- Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Emiliania huxleyi is a cosmopolitan coccolithophore widespread in temperate oceans. This unicellular photoautotroph forms massive recurring blooms that play an important role in large biogeochemical cycles of carbon and sulfur, which play a role in climate change. The mechanism of bloom formation and demise, controlled by giant viruses that routinely infect these blooms, is poorly understood. We generated a pan-transcriptome of E. huxleyi, derived from three strains with different susceptibility to viral infection. Expression profiling of E. huxleyi sensitive and resistant strains showed major basal differences, including many genes that are induced upon viral infection. This suggests that basal gene expression can affect the host metabolic state and the susceptibility of E. huxleyi to viruses. Due to its ecological importance, the pan-transcriptome and its protein translation, applicable to many E. huxleyi strains, is a powerful resource for investigation of eukaryotic microbial communities.
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