ArticleMolecular cancer research : MCR2022
Clinical and Functional Significance of TP53 Exon 4-Intron 4 Splice Junction Variants.
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Article in Molecular cancer research : MCR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 14 citations in OpenAlex.
- Beyond Invariable Sites: Using Evolutionary Stasis to Map Multilayered Constraints on the Evolution of Viral and Mammalian Genomes.Genome biology and evolution · 2026Article
- Associative memory plays a role in ER-1α positive breast cancers.Cell death and differentiation · 2026Review
- Homozygous TP53 alterations: a case of a biallelic splice variant and a brief review of the literature.Familial cancer · 2026Review
- Beyond Invariable Sites: Using Evolutionary Stasis to Map Multi-Layered Constraints on the Evolution of Viral and Mammalian Genomes.bioRxiv : the preprint server for biology · 2026Article
- Synonymous and non-synonymous variants at splice junctions can disrupt splicing and are frequently linked to disease associated loss of function genes.BMC genomics · 2025Article
- Article
- Microglial Inflammatory Response in the Glioblastoma Microenvironment in Preclinical Models.Molecular neurobiology · 2025Article
- Transfer Learning for Survival-based Clustering of Predictors with an Application tobioRxiv : the preprint server for biology · 2025Article
- TP53-Mutated Acute Myeloid Leukemia and Blast Phase Myeloproliferative Neoplasm: Distinct Mutation Leads to Poorer Prognosis.European journal of haematology · 2025Article
- Heterochronic pelvic high-grade myxoinflammatory fibroblastic sarcoma and uterine endometroid carcinoma harboring common gene mutations: a rare case report with genomic analysis.Diagnostic pathology · 2025Article
- TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact.NPJ genomic medicine · 2025Article
- Utility of the Base Editing System for Introducing Drug-Resistant Gene Mutations Into Human Leukemia Cellular Models.Cureus · 2025Article
- Personalized screening strategies forLancet regional health. Americas · 2025Article
- Clinical and functional analysis of the germlineCold Spring Harbor molecular case studies · 2023Article
- The role of alternative pre-mRNA splicing in cancer progression.Cancer cell international · 2023Review
- Intronic GermlineJCO precision oncology · 2023Article
- Hereditary Endocrine Tumor Registries.Journal of the Endocrine Society · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 3 countries.
Emilia M PintoDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee. emilia.pinto@stjude.org raul.ribeiro@stjude.org gerard.zambetti@stjude.org.ORCID 0000-0001-5567-000X
Kara N MaxwellDepartment of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-8192-4202
Hadeel HalalshehKing Hussein Cancer Center, Amman, Jordan.ORCID 0000-0003-4803-1976
Aaron PhillipsDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Jacquelyn PowersDepartment of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Suzanne MacFarlandDepartment of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-5894-6403
Michael F WalshDepartment of Pediatrics and Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-5006-6778
Kelsey BreenDepartment of Pediatrics and Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-7302-1564
Maria N FormigaDepartment of Oncogenetics, A.C. Camargo Center, Sao Paulo, Brazil.ORCID 0000-0002-1187-1384
Richard KriwackiDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0002-9798-6018
Kim E NicholsDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0002-5581-6555
Roya MostafaviDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0002-6606-2920
Jinling WangDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0003-3028-1133
Michael R ClayDepartment of Pathology, University of Colorado, Boulder, Colorado.ORCID 0000-0003-1659-8927
Carlos Rodriguez-GalindoDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.ORCID 0000-0002-2360-8946
Raul C RibeiroDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee. emilia.pinto@stjude.org raul.ribeiro@stjude.org gerard.zambetti@stjude.org.ORCID 0000-0002-9956-5647
Gerard P ZambettiDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee. emilia.pinto@stjude.org raul.ribeiro@stjude.org gerard.zambetti@stjude.org.ORCID 0000-0002-0929-5007
St. Jude Children's Research Hospital · USUniversity of Pennsylvania · USMemorial Sloan Kettering Cancer Center · USAC Camargo Hospital · BRKing Hussein Cancer Center · JOUniversity of Colorado Boulder · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MViral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9MNCI NIH HHS P30 CA008748NCI NIH HHS P30 CA021765
Abstract
Germline
Indexed as
ExonsGenetic VariationHumansIntronsTumor Suppressor Protein p53TP53 protein, humanTumor Suppressor Protein p53
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.