Evidence map›Paper›PMID 34675112›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Coreline N Burggraaff, Jakoba J Eertink, Pieternella J Lugtenburg, Otto S Hoekstra, Anne I J Arens, Bart de Keizer, Martijn W Heymans, Bronno van der Holt, Sanne E Wiegers, Simone Pieplenbosch and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. [Primary imaging diagnostics of lymphomas].Radiologie (Heidelberg, Germany) · 2025
    Review
  4. Article
  5. Quantitative imaging in medicine and surgery · 2025
    Article
  6. Review
  7. PET/CT Biomarkers Enable Risk Stratification of Patients with Relapsed/Refractory Diffuse Large B-cell Lymphoma Enrolled in the LOTIS-2 Clinical Trial.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  8. Review
  9. Observational
  10. Prognostic Value ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  11. Semi-automatedComputational and structural biotechnology journal · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Coreline N BurggraaffDepartment of Hematology, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Jakoba J EertinkDepartment of Hematology, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Pieternella J LugtenburgDepartment of Hematology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Otto S HoekstraDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Anne I J ArensDepartment of Radiology, Nuclear Medicine, and Anatomy, Radboud University Medical Center, Nijmegen, The Netherlands.
Bart de KeizerDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Martijn W HeymansDepartment of Epidemiology and Data Science, Amsterdam UMC, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; and.
Bronno van der HoltDepartment of Hematology, HOVON Data Center, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Sanne E WiegersDepartment of Hematology, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Simone PieplenboschDepartment of Hematology, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Ronald BoellaardDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Henrica C W de VetDepartment of Epidemiology and Data Science, Amsterdam UMC, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; and.
Josée M ZijlstraDepartment of Hematology, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; j.zijlstra@amsterdamumc.nl.
HOVON Imaging Working Group and the HOVON Lymphoma Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to determine the added value of baseline metabolic tumor volume (MTV) and interim PET (I-PET) to the age-adjusted international prognostic index (aaIPI) to predict 2-y progression-free survival (PFS) in diffuse large B-cell lymphoma. Secondary objectives were to investigate optimal I-PET response criteria (using Deauville score [DS] or quantitative change in SUV

Indexed as

Fluorodeoxyglucose F18Lymphoma, Large B-Cell, DiffuseAdultAntineoplastic Combined Chemotherapy ProtocolsHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyPrognosisRituximabFluorodeoxyglucose F18RituximabDeauville scoreDLBCLmetabolic tumor volumePETΔSUVmax

Identifiers

PMID34675112
PMCPMC9258573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.