Evidence map›Paper›PMID 34675064›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2022

Dietary Pterostilbene for MTA1-Targeted Interception in High-Risk Premalignant Prostate Cancer.

Rutu Hemani, Ishani Patel, Ninad Inamdar, Gisella Campanelli, Virginia Donovan, Avinash Kumar, Anait S Levenson

Open access · bronzeAbstract read
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rutu HemaniArnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York.ORCID 0000-0002-5150-4247
Ishani PatelArnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York.
Ninad InamdarArnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York.
Gisella CampanelliArnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York.
Virginia DonovanNew York University Winthrop Hospital, Mineola, New York.
Avinash KumarArnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York. anait.levenson@liu.edu avinash.kumar@liu.edu.ORCID 0000-0001-8132-5939
Anait S LevensonCancer Institute, University of Mississippi Medical Center, Jackson, Mississippi. anait.levenson@liu.edu avinash.kumar@liu.edu.
Long Island University · USWinthrop-University Hospital · US

Funding

MTA1- targeted strategies for prostate cancer managementR15CA216070 · NCI · LONG ISLAND UNIVERSITY BROOKLYN CAMPUS · PI LEVENSON, ANAIT S · 2018 to 2020
$459k
NCI NIH HHS R15 CA216070
6 · The paper itself

Abstract

Prostate cancer remains one of the most prevalent cancers in aging men. Active surveillance subpopulation of patients with prostate cancer includes men with varying cancer risk categories of precancerous disease due to prostatic intraepithelial neoplasia (PIN) heterogeneity. Identifying molecular alterations associated with PIN can provide preventable measures through finding novel pharmacologic targets for cancer interception. Targeted nutritional interception may prove to be the most appropriate chemoprevention for intermediate- and high-risk active surveillance patients. Here, we have generated two prostate-specific transgenic mouse models, one overexpressing MTA1 (

Indexed as

Precancerous ConditionsProstatic Intraepithelial NeoplasiaProstatic NeoplasmsAnimalsCell Line, TumorDietHumansMaleMiceRepressor ProteinsStilbenesTrans-ActivatorsMTA1 protein, humanpterostilbeneRepressor ProteinsStilbenesTrans-Activators

Identifiers

PMID34675064
PMCPMC8828670
OpenAlexW3205753537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.