ArticleJournal of the American Society of Nephrology : JASN2021
Intermediate Renal Outcomes, Kidney Failure, and Mortality in Obese Kidney Donors.
Article in Journal of the American Society of Nephrology : JASN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Expanding the living kidney donor pool: outcomes of robotic donor nephrectomy in obese versus non-obese donors.Surgical endoscopy · 2026Article
- Comparison of Laparoscopic and Hand-assisted Live Donor Nephrectomy: An Analysis of NSQIP Transplant.Transplantation direct · 2026Article
- Long-Term Kidney and Maternal Outcomes After Pregnancy in Living Kidney Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Diabetes-free survival among living kidney donors and non-donors with obesity: A longitudinal cohort study.PloS one · 2022Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is associated with the two archetypal kidney disease risk factors: hypertension and diabetes. Concerns that the effects of diabetes and hypertension in obese kidney donors might be magnified in their remaining kidney have led to the exclusion of many obese candidates from kidney donation.
methodsWe compared mortality, diabetes, hypertension, proteinuria, reduced eGFR and its trajectory, and the development of kidney failure in 8583 kidney donors, according to body mass index (BMI). The study included 6822 individuals with a BMI of <30 kg/m
resultsObese donors were more likely than nonobese donors to develop diabetes, hypertension, and proteinuria. The increase in eGFR in obese versus nonobese donors was significantly higher in the first 10 years (3.5 ml/min per 1.73m
conclusionsObesity in kidney donors, as in nondonors, is associated with increased risk of developing diabetes and hypertension. The absolute risk of ESKD is small and the risk of death is comparable to that of nonobese donors.
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