Evidence map›Paper›PMID 34674756›Full record

ArticleAntimicrobial resistance and infection control2021

Nosocomial cluster of carbapenemase-producing Enterobacter cloacae in an intensive care unit dedicated COVID-19.

Guillaume Miltgen, Thomas Garrigos, Pascal Cholley, Marine Deleume, Nicolas Allou, Jérôme Allyn, David A Wilkinson, Nathalie Lugagne, Olivier Belmonte, Xavier Bertrand and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  9. BMJ case reports · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 3 countries.

Guillaume MiltgenLaboratoire de Bactériologie, CHU Félix Guyon, Allée des Topazes, 97400, Saint-Denis, La Réunion, France. guillaume.miltgen@chu-reunion.fr.ORCID 0000-0002-5178-9879
Thomas GarrigosLaboratoire de Bactériologie, CHU Félix Guyon, Allée des Topazes, 97400, Saint-Denis, La Réunion, France.
Pascal CholleyService d'Hygiène Hospitalière, CHU Jean Minjoz, Besançon, France.
Marine DeleumeLaboratoire de Bactériologie, CHU Félix Guyon, Allée des Topazes, 97400, Saint-Denis, La Réunion, France.
Nicolas AllouService de Réanimation Polyvalente, CHU Félix Guyon, Saint-Denis, La Réunion, France.
Jérôme AllynService de Réanimation Polyvalente, CHU Félix Guyon, Saint-Denis, La Réunion, France.
David A WilkinsonUMR PIMIT, Processus Infectieux en Milieu Insulaire Tropical, CNRS 9192, INSERM U1187, IRD 249, Université de La Réunion, Sainte-Clotilde, La Réunion, France.
Nathalie LugagneService d'hygiène hospitalière, CHU Félix Guyon, Saint-Denis, La Réunion, France.
Olivier BelmonteLaboratoire de Bactériologie, CHU Félix Guyon, Allée des Topazes, 97400, Saint-Denis, La Réunion, France.
Xavier BertrandService d'Hygiène Hospitalière, CHU Jean Minjoz, Besançon, France.
Didier HocquetService d'Hygiène Hospitalière, CHU Jean Minjoz, Besançon, France.
Patrick MavinguiUMR PIMIT, Processus Infectieux en Milieu Insulaire Tropical, CNRS 9192, INSERM U1187, IRD 249, Université de La Réunion, Sainte-Clotilde, La Réunion, France.
Centre Hospitalier Universitaire de La Réunion · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Concomitant prevention of SARS-CoV-2 and extensively drug-resistant bacteria transmission is a difficult challenge in intensive care units dedicated to COVID-19 patients. We report a nosocomial cluster of four patients carrying NDM-1 plasmid-encoded carbapenemase-producing Enterobacter cloacae. Two main factors may have contributed to cross-transmission: misuse of gloves and absence of change of personal protective equipment, in the context of COVID-19-associated shortage. This work highlights the importance of maintaining infection control measures to prevent CPE cross-transmission despite the difficult context and that this type of outbreak can potentially involve several species of Enterobacterales.

Indexed as

Bacterial Proteinsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCoinfectionCOVID-19Cross InfectionDisease OutbreaksEnterobacter cloacaeEnterobacteriaceae InfectionsHumansInfection ControlIntensive Care UnitsPersonal Protective EquipmentSARS-CoV-2Bacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemaseCOVID-19Cross transmissionEnterobacter cloacaeIntensive care unitPersonal protective equipment

Identifiers

PMID34674756
PMCPMC8529563
OpenAlexW3205400141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.