Evidence map›Paper›PMID 34674630›Full record

ArticleBMC bioinformatics2021

A sui generis QA approach using RoBERTa for adverse drug event identification.

Harshit Jain, Nishant Raj, Suyash Mishra

Abstract read
In one paragraph

Article in BMC bioinformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Transformer models in biomedicine.BMC medical informatics and decision making · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Harshit Jain *ZS Associates, Bengaluru, India.
Nishant Raj *University of Massachusetts Amherst, Amherst, USA. nishantraj@umass.edu.ORCID http://orcid.org/0000-0002-7294-9026
Suyash Mishra *ZS Associates, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtraction of adverse drug events from biomedical literature and other textual data is an important component to monitor drug-safety and this has attracted attention of many researchers in healthcare. Existing works are more pivoted around entity-relation extraction using bidirectional long short term memory networks (Bi-LSTM) which does not attain the best feature representations.

resultsIn this paper, we introduce a question answering framework that exploits the robustness, masking and dynamic attention capabilities of RoBERTa by a technique of domain adaptation and attempt to overcome the aforementioned limitations. With formulation of an end-to-end pipeline, our model outperforms the prior work by 9.53% F1-Score.

conclusionAn end-to-end pipeline that leverages state of the art transformer architecture in conjunction with QA approach can bolster the performances of entity-relation extraction tasks in the biomedical domain. In particular, we believe our research would be helpful in identification of potential adverse drug reactions in mono as well as combination therapy related textual data.

Indexed as

Drug-Related Side Effects and Adverse ReactionsNeural Networks, ComputerHumansAdverse drug eventEntity-relation extractionHealthcareQuestion-answeringRoBERTa

Identifiers

PMID34674630
PMCPMC8529716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.