Evidence map›Paper›PMID 34674546›Full record

ArticleBiomarkers in medicine2021

Characterization and standardization of multiassay platforms for four commonly studied traumatic brain injury protein biomarkers: a TBI Endpoints Development Study.

George Anis Sarkis, Tian Zhu, Zhihui Yang, Xue Li, Yuan Shi, Richard Rubenstein, Richard A Yost, Geoffrey T Manley, Kevin K Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomarkers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

George Anis SarkisDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0001-6835-0769
Tian ZhuDepartment of Emergency Medicine, University of Florida, 1149 Newell Drive, L4-100, Gainesville, FL 32611, USA.
Zhihui YangDepartment of Emergency Medicine, University of Florida, 1149 Newell Drive, L4-100, Gainesville, FL 32611, USA.
Xue LiDepartment of Emergency Medicine, University of Florida, 1149 Newell Drive, L4-100, Gainesville, FL 32611, USA.
Yuan ShiDepartment of Pediatrics, Daping Hospital, Chongqing, Third Military Medical University, Chongqing, China.ORCID 0000-0002-4227-3643
Richard RubensteinDepartment of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203-2098, USA.
Richard A YostDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Geoffrey T ManleyDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
Kevin K WangDepartment of Emergency Medicine, University of Florida, 1149 Newell Drive, L4-100, Gainesville, FL 32611, USA.

Funding

Transforming Research and Clinical Knowledge in Traumatic Brain InjuryU01NS086090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIAZ-ARRASTIA, RAMON, GIACINO, JOSEPH THOMAS · 2013 to 2017
$19.1M
NINDS NIH HHS U01 NS086090
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Endpoint DeterminationAntigensBiological AssayBiomarkersBrain Injuries, TraumaticCase-Control StudiesGlial Fibrillary Acidic ProteinHumansRecombinant ProteinsReference StandardsS100 Calcium Binding Protein beta Subunittau ProteinsUbiquitin ThiolesteraseAntigensBiomarkersGlial Fibrillary Acidic ProteinRecombinant ProteinsS100B protein, humanS100 Calcium Binding Protein beta Subunittau ProteinsUbiquitin ThiolesteraseUCHL1 protein, humanbiomarker qualificationGFAPneurodegenerationprotein biomarkersS100BTautraumatic brain injuryUCH-L1

Identifiers

PMID34674546
PMCPMC8739397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.