Evidence map›Paper›PMID 34674246›Full record

ArticleDevelopmental psychobiology2021

A single-session behavioral protocol for successful event-related potential recording in children with neurodevelopmental disorders.

Maggie W Guy, Conner J Black, Abigail L Hogan, Ramsey E Coyle, John E Richards, Jane E Roberts

Abstract read
In one paragraph

Article in Developmental psychobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maggie W GuyDepartment of Psychology, Loyola University Chicago, Chicago, Illinois, 60660, USA.ORCID 0000-0003-2326-6218
Conner J BlackDepartment of Psychology, University of South Carolina, Columbia, South Carolina, USA.
Abigail L HoganDepartment of Psychology, University of South Carolina, Columbia, South Carolina, USA.
Ramsey E CoyleDepartment of Psychology, University of South Carolina, Columbia, South Carolina, USA.
John E RichardsDepartment of Psychology, University of South Carolina, Columbia, South Carolina, USA.
Jane E RobertsDepartment of Psychology, University of South Carolina, Columbia, South Carolina, USA.

Funding

Emergence, Stability and Predictors of Anxiety in Fragile X SyndromeR01MH107573 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI Abigail Lee Hogan · 2016 to 2026
$6.1M
Supplement to The Emergence and Stability of Autism in Fragile X SyndromeR01MH090194 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ROBERTS, JANE E · 2011 to 2020
$5.4M
The Development of Sustained Attention in InfantsR37HD018942 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RICHARDS, JOHN E · 2007 to 2016
$4.5M
The development of sustained attention in infantsR01HD018942 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RICHARDS, JOHN E · 1988 to 2021
$4.2M
NICHD NIH HHS R01 HD018942NICHD NIH HHS R37 HD018942NIMH NIH HHS R01 MH090194NIMH NIH HHS R01MH090194NIMH NIH HHS R01 MH107573NIMH NIH HHS R01MH107573
6 · The paper itself

Abstract

Event-related potentials (ERPs) are an ideal tool for measuring neural responses in a wide range of participants, including children diagnosed with neurodevelopmental disorders (NDDs). However, due to perceived barriers regarding participant compliance, much of this work has excluded children with low IQ and/or reduced adaptive functioning, significant anxiety symptoms, and/or sensory processing difficulties, including heterogeneous samples of children with autism spectrum disorder (ASD) and children with fragile X syndrome (FXS). We have developed a behavioral support protocol designed to obtain high-quality ERP data from children in a single session. Using this approach, ERP data were successfully collected from participants with ASD, FXS, and typical development (TD). Higher success rates were observed for children with ASD and TD than children with FXS. Unique clinical-behavioral characteristics were associated with successful data collection across these groups. Higher chronological age, nonverbal mental age, and receptive language skills were associated with a greater number of valid trials completed in children with ASD. In contrast, higher language ability, lower autism severity, increased anxiety, and increased sensory hyperresponsivity were associated with a greater number of valid trials completed in children with FXS. This work indicates that a "one-size-fits-all" approach cannot be taken to ERP research on children with NDDs, but that a single-session paradigm is feasible and is intended to promote increased representation of children with NDDs in neuroscience research through development of ERP methods that support inclusion of diverse and representative samples.

Indexed as

Autism Spectrum DisorderFragile X SyndromeAnxiety DisordersAptitudeChildEvoked PotentialsHumansautism spectrum disorderchildevent-related potentialsfragile X syndrome

Identifiers

PMID34674246
PMCPMC9523962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.