Evidence map›Paper›PMID 34674047›Full record

ReviewCurrent neurology and neuroscience reports2021

Cranioplasty Following Severe Traumatic Brain Injury: Role in Neurorecovery.

Baris Ozoner

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06895109 (Evaluation of Improvement in Cognitive Functions and Psychological Aspects in Patients With Severe Acquired Brain Injury After Cranioplasty), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06895109 active not recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of Improvement in Cognitive Functions and Psychological Aspects in Patients With Severe Acquired Brain Injury After Cranioplasty

Typeobservational_patient_registrySponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2025 to 2026Enrolled20ConditionsBrain Injury, Neuropsychological Deficits, Cranioplasty, Cognitive Deficit Following Brain LesionsArmsimprovement of cognitive functions and psychological aspects
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Complications of Alloplastic Graft Materials Used in Cranioplasty: Systematic Review and Network Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2026
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  15. Craniectomy and Cranioplasty Effects on Balance and Gait in Rehabilitation: A Retrospective Study.Archives of rehabilitation research and clinical translation · 2024
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Baris OzonerDepartment of Neurosurgery, Kartal Dr. Lutfi Kirdar Research and Education Hospital, University of Health Sciences, Istanbul, Turkey. drbarisozoner@gmail.com.ORCID http://orcid.org/0000-0003-0534-2766
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewDecompressive craniectomy (DC) is a life-saving procedure performed in refractory intracranial pressure increase and mass lesion due to severe traumatic brain injury (TBI). Cranioplasty primarily intends to maintain cerebral protection and reconstruct aesthetic appearance. Also, cranioplasty can enable neurological rehabilitation and potentially augment neurological recovery. This article reviews recent studies on the effect of cranioplasty on neurological recovery in severe TBI. RECENT

findingsRecent findings suggested that cranioplasty has the potential to enhance neurological recovery after severe TBI. Cranioplasty may alleviate cognitive and functional deficits by reinstating the regular cerebrospinal fluid dynamics and improving brain perfusion. Analyses on the effects of cranioplasty timing on neurological recovery likely favor early cranioplasty. Also, materials used during cranioplasty, autologous and exogenous, were suggested to have similar effects in recovery. Although neurological therapy of TBI patients is still a serious challenge, recent findings represent the possible enhancing effect of cranioplasty on neurological recovery.

Indexed as

Brain InjuriesBrain Injuries, TraumaticDecompressive CraniectomyHumansRetrospective StudiesSkullTreatment OutcomeAutologous bone graftCognitive outcomeCranioplastyDecompressive craniectomyEarly cranioplastyFunctional outcomeNeurological recoveryOutcomeTraumatic brain injury

Identifiers

PMID34674047
OpenAlexW3207426259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.