Evidence map›Paper›PMID 34673866›Full record

ArticleChemical communications (Cambridge, England)2021

Switching the aptamer attachment geometry can dramatically alter the signalling and performance of electrochemical aptamer-based sensors.

Alejandro Chamorro-Garcia, Gabriel Ortega, Davide Mariottini, Joshua Green, Francesco Ricci, Kevin W Plaxco

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alejandro Chamorro-GarciaCenter for Bioengineering, University of California Santa Barbara, Santa Barbara, CA 93106, USA. kwp@chem.ucsb.edu.ORCID http://orcid.org/0000-0003-0953-5848
Gabriel OrtegaCenter for Bioengineering, University of California Santa Barbara, Santa Barbara, CA 93106, USA. kwp@chem.ucsb.edu.ORCID http://orcid.org/0000-0002-7126-9096
Davide MariottiniDipartimento di Scienze e Tecnologie Chimiche, University of Rome, Tor Vergata, Via della Ricerca Scientifica, Rome 00133, Italy.ORCID http://orcid.org/0000-0001-6121-6428
Joshua GreenDepartment of Chemistry and Biochemistry, University of California Santa Barbara (UCSB), Santa Barbara, CA 93106, USA.ORCID http://orcid.org/0000-0002-9376-1532
Francesco RicciDipartimento di Scienze e Tecnologie Chimiche, University of Rome, Tor Vergata, Via della Ricerca Scientifica, Rome 00133, Italy.ORCID http://orcid.org/0000-0003-4941-8646
Kevin W PlaxcoCenter for Bioengineering, University of California Santa Barbara, Santa Barbara, CA 93106, USA. kwp@chem.ucsb.edu.ORCID http://orcid.org/0000-0003-4772-8771

Funding

Bio-electrochemical detectors for in vivo continuous monitoringR01EB022015 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI KIPPIN, TOD EDWARD, PLAXCO, KEVIN W · 2017 to 2025
$4.6M
Feedback controlled, ultra-high-precision drug deliveryR01AI145206 · NIAID · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI PLAXCO, KEVIN W · 2019 to 2023
$2.0M
NIAID NIH HHS R01 AI145206NIBIB NIH HHS R01 EB022015
6 · The paper itself

Abstract

Electrochemical aptamer-based (EAB) sensors, composed of an electrode-bound DNA aptamer with a redox reporter on the distal end, offer the promise of high-frequency, real-time molecular measurements in complex sample matrices and even

Indexed as

Biosensing TechniquesElectrochemical TechniquesAptamers, NucleotideCocaineDoxorubicinElectrodesOxidation-ReductionVancomycinAptamers, NucleotideCocaineDoxorubicinVancomycin

Identifiers

PMID34673866
PMCPMC9703874

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.