Evidence map›Paper›PMID 34673833›Full record

ReviewPLoS pathogens2021

Pathogenesis insights from an ancient and ubiquitous spirochete.

Jenifer Coburn, Mathieu Picardeau, Christopher W Woods, Timothy Veldman, David A Haake

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Seropositivity for PathogenicTropical medicine and infectious disease · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Degradation of p0071 and p120-catenin during adherens junction disassembly byFrontiers in cellular and infection microbiology · 2023
    Article
  9. Article
  10. Observational
  11. Motility of the Zoonotic SpirocheteInternational journal of molecular sciences · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jenifer CoburnMedical College of Wisconsin, Milwaukee, Wisconsin, United States of America.ORCID 0000-0001-6460-2017
Mathieu PicardeauPasteur Institute, Paris, France.
Christopher W WoodsDuke University Medical Center, Durham, North Carolina, United States of America.ORCID 0000-0001-7240-2453
Timothy VeldmanDuke University Medical Center, Durham, North Carolina, United States of America.
David A HaakeVA Greater Los Angeles Healthcare System, Los Angeles, California, United States of America.ORCID 0000-0002-8468-6526

Funding

Leptospira interrogans Interactions with Endothelial CellsR01AI112920 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI COBURN, JENIFER L · 2014 to 2017
$1.5M
Mechanisms of Leptospira interrogans interactions with the vascular endothelium in vivoR21AI147573 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI COBURN, JENIFER L · 2020 to 2021
$435k
Virulence Proteins of Pathogenic Leptospira SpeciesR21AI128560 · NIAID · BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE · PI HAAKE, DAVID A · 2017 to 2018
$357k
The Leptospiral Outer Membrane Proteome & ImmunityI01BX002003 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI MATSUNAGA, JAMES · 2014 to 2022
–
BLRD VA I01 BX002003NIAID NIH HHS R01 AI112920NIAID NIH HHS R21 AI128560NIAID NIH HHS R21 AI147573
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LeptospirosisAnimalsHumansLeptospira

Identifiers

PMID34673833
PMCPMC8530280

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.