Evidence map›Paper›PMID 34673755›Full record

Observational studyNature2021

Immunogenicity and efficacy of          heterologous ChAdOx1-BNT162b2 vaccination.

Bruno Pozzetto, Vincent Legros, Sophia Djebali, Véronique Barateau, Nicolas Guibert, Marine Villard, Loïc Peyrot, Omran Allatif, Jean-Baptiste Fassier, Amélie Massardier-Pilonchéry and 16 more

Registry-linked trialOpen access · hybridAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04341142 (Assessment of Serological Techniques for Screening Patients Regarding COVID-19-COVID-SER), which is not on this map. Cited by 146 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
146citing papers in PubMed, 5 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04341142 naactive not recruitingnot on this map

Assessment of Serological Techniques for Screening Patients Regarding COVID-19-COVID-SER

TypeinterventionalSponsorHospices Civils de LyonRan2020 to 2026Enrolled550ConditionsCoV2 Positive CaregiversArmsSerological tests will be applied on patients blood sampling
3 · Its place in the literature

Who cites it

146 citing papers in PubMed, 5 syntheses or guidelines pooled it, 230 citations in OpenAlex.

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86 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 2 institutions in 1 country.

Bruno Pozzetto *CIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.
Vincent Legros *CIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.ORCID http://orcid.org/0000-0002-6118-7564
Sophia Djebali *CIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.ORCID http://orcid.org/0000-0002-0567-5387
Véronique Barateau *CIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.
Nicolas GuibertOccupational Health and Medicine Department, Hospices Civils de Lyon, Université Claude Bernard Lyon1, Ifsttar, UMRESTTE, UMR T_9405, Université de Lyon, Lyon, France.ORCID http://orcid.org/0000-0002-1192-8301
Marine VillardCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.ORCID http://orcid.org/0000-0002-3905-8993
Loïc PeyrotCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.
Omran AllatifCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.ORCID http://orcid.org/0000-0002-2539-972X
Jean-Baptiste FassierOccupational Health and Medicine Department, Hospices Civils de Lyon, Université Claude Bernard Lyon1, Ifsttar, UMRESTTE, UMR T_9405, Université de Lyon, Lyon, France.
Amélie Massardier-PilonchéryOccupational Health and Medicine Department, Hospices Civils de Lyon, Université Claude Bernard Lyon1, Ifsttar, UMRESTTE, UMR T_9405, Université de Lyon, Lyon, France.
Karen Brengel-PesceJoint Research Unit Civils Hospices of Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France.
Melyssa Yaugel-NovoaCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.
Solène DenollyCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.ORCID http://orcid.org/0000-0003-1739-0079
Bertrand BosonCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.ORCID http://orcid.org/0000-0003-1920-5172
Thomas BourletCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.
Antonin BalCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.
Martine ValetteVirology Laboratory, Institute of Infectious Agents, Laboratory Associated with the National Reference Centre for Respiratory Viruses, Hospices Civils de Lyon, Lyon, France.
Thibault AndrieuCentre de Recherche en Cancérologie de Lyon, INSERM U1052, CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon 1, Centre Léon Bérard, Lyon, France.
Bruno LinaCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France.
Covid-Ser study group
François-Loïc CossetCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France. flcosset@ens-lyon.fr.ORCID http://orcid.org/0000-0001-8842-3726
Stéphane PaulCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France. stephane.paul@chu-st-etienne.fr.ORCID http://orcid.org/0000-0002-8830-4273
Thierry DefranceCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France. thierry.defrance@inserm.fr.ORCID http://orcid.org/0000-0002-6943-358X
Jacqueline MarvelCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France. jacqueline.marvel@inserm.fr.ORCID http://orcid.org/0000-0001-6241-459X
Thierry WalzerCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France. thierry.walzer@inserm.fr.ORCID http://orcid.org/0000-0002-0857-8179
Sophie Trouillet-AssantCIRI (Centre International de Recherche en Infectiologie), Université de Lyon, Université Claude Bernard Lyon 1, INSERM U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, France. sophie.assant@chu-lyon.fr.
Université Claude Bernard Lyon 1 · FRHospices Civils de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following severe adverse reactions to the AstraZeneca ChAdOx1-S-nCoV-19 vaccine

Indexed as

AdultAntibodies, NeutralizingBNT162 VaccineChAdOx1 nCoV-19COVID-19FemaleFranceHospitals, UniversityHumansImmunologic MemoryIncidenceMaleMemory B CellsMemory T CellsMiddle AgedSARS-CoV-2Antibodies, NeutralizingBNT162 VaccineChAdOx1 nCoV-19Spike Glycoprotein, Coronavirusspike protein, SARS-CoV-2

Identifiers

PMID34673755
OpenAlexW3189962012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.