SynthesisDiabetes & metabolic syndrome
Impact of metabolic and cardiovascular disease on COVID-19 mortality: A systematic review and meta-analysis.
Synthesis in Diabetes & metabolic syndrome. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Risk factors for long COVID among participants of a population-based study in urban and rural Kenya, 2021.BMC public health · 2025Article
- Comprehensive assessment of COVID-19 case fatality rate and influential factors in Khuzestan Province, Iran: a two-year study.Journal of health, population, and nutrition · 2024Article
- Impact of comorbidities on COVID-19 mortality in hospitalized women: Insights from the metropolitan area of the Valley of Mexico from 2020 to 2022.IJID regions · 2024Article
- Fragmentation of the QRS Complex Is Associated with Right Ventricular Dilatation and Mortality in Critically Unwell Coronavirus Disease 2019 Patients.Anatolian journal of cardiology · 2024Article
- COVID-19-related hospital admission in spouses of partners in at-risk occupations.Scandinavian journal of work, environment & health · 2023Article
- Associations between mortality from COVID-19 and other causes: A state-level analysis.PloS one · 2023Article
- A study on the morbid histopathological changes in COVID-19 patients with or without comorbidities using minimally invasive tissue sampling.Journal of medical virology · 2023Article
- Understanding outcomes of emergency aortic dissection repair during COVID-19 pandemic: What lessons have we learnt?Journal of cardiac surgery · 2022Article
- Neuropilin (NRPs) Related Pathological Conditions and Their Modulators.International journal of molecular sciences · 2022Review
- Serological Response and Relationship with Gender-Sensitive Variables among Healthcare Workers after SARS-CoV-2 Vaccination.Journal of personalized medicine · 2022Article
- Association between mortality and cardiovascular diseases in the vulnerable Mexican population: A cross-sectional retrospective study of the COVID-19 pandemic.Frontiers in public health · 2022Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThis meta-analysis aims to highlight the impact of cardio-metabolic comorbidities on COVID-19 severity and mortality.
methodsA thorough search on major online databases was done for studies describing the clinical outcomes of COVID-19 patients. We used random-effects model to compute pooled estimates for critical or fatal disease.
resultsA total of 20,475 patients from 33 eligible studies were included. Maximum risk of development of critical or fatal COVID-19 disease was seen in patients with underlying cardiovascular disease [OR: 3.44, 95% CI: 2.65-4.48] followed by chronic lung disease, hypertension and diabetes mellitus. Of the total cases, 64% had one of the four comorbidities with the most prevalent being hypertension with a pooled prevalence of 27%.
conclusionsPresence of comorbidities like cardiovascular disease, chronic lung disease, hypertension and diabetes mellitus led to a higher risk of development of critical or fatal COVID-19 disease, with maximum risk seen with underlying cardiovascular disease.
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