ReviewNeuroImage2021
Tractography methods and findings in brain tumors and traumatic brain injury.
Review in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 90 citations in OpenAlex.
- Quantitative Navigated Transcranial Magnetic Stimulation Motor Mapping and nTMS-Guided Corticospinal Tractography in Healthy Individuals and Patients with Motor-Eloquent Brain Tumors.Brain sciences · 2026Article
- Network-level disconnectivity tracks poststroke depressive symptom improvement.Psychiatry and clinical neurosciences · 2026Observational
- Creativity: a (white) matter of connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Thiol-Based Neuroprotective Copolymers Acutely Restore Redox Metabolism and Mediate Vasogenic Edema in a Mouse Model of Traumatic Brain Injury.Macromolecular bioscience · 2026Article
- Hadamard-encoded scattered light imaging for faster, signal-enhanced mapping of brain fiber orientations.Biomedical optics express · 2026Article
- Disrupted integration-segregation balance in the intact hemisphere in chronic spatial neglect.Brain structure & function · 2026Article
- Pitch as a Shared Code for Music and Speech: Behavioral and Neural Evidence From Stroke Patients.Brain and behavior · 2026Article
- Unilateral inferior olivary hypertrophy in a patient with primary progressive apraxia of speech.Neuroimage. Reports · 2026Article
- CNNT-Net: a novel deep learning-based framework for estimating high-quality fiber orientation distributions from single-shell dMRI.Physical and engineering sciences in medicine · 2026Article
- Primary Somatosensory to Motor Cortex Microstructural Connectivity Predicts the Mu-Rhythm Phase Effect on Corticospinal Excitability: An EEG-TMS Study.Human brain mapping · 2026Article
- Causal dependencies between frontal and temporal lobe regions underlying word search and retrieval.bioRxiv : the preprint server for biology · 2026Article
- Bridging the microstructural gap in human connectomics using hierarchical phase-contrast tomography as a reference for diffusion MRI in the human brain.bioRxiv : the preprint server for biology · 2026Article
- Evaluation of tractography parameters for dentato-rubro-thalamic tract reconstruction during pediatric posterior fossa tumor surgery.Magma (New York, N.Y.) · 2026Article
- Differential tractography suggests a "left-to-whole" white matter degeneration pattern in aging.Brain imaging and behavior · 2026Article
- Exploring the 3D architecture of brain tissue using digital holographic microscopy.Biomedical optics express · 2026Article
- A voxel-based quantitative framework for analyzing the spatial redistribution and directionality of recurrence in glioblastoma.Journal of neuro-oncology · 2026Article
- A non-local diffusion magnetic resonance imaging tract density biomarker to stratify, predict, and interpret survival rates in human glioblastoma.Neuro-oncology · 2026Article
- Association of Fractional Anisotropy in White Matter Bundles with Plasma Biomarkers of Neurodegeneration and Glial Reactivity in Individuals with Cognitive Complaints without dementia.Research square · 2026Article
- Advanced diffusion MRI tractography for radiotherapy planning in pediatric brain tumors: A feasibility study.Physics and imaging in radiation oncology · 2026Article
- Eloquent glioma resection assisted by brain connectomics: A new tool for awake neurosurgery.Surgical neurology international · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
White matter fiber tracking using diffusion magnetic resonance imaging (dMRI) provides a noninvasive approach to map brain connections, but improving anatomical accuracy has been a significant challenge since the birth of tractography methods. Utilizing tractography in brain studies therefore requires understanding of its technical limitations to avoid shortcomings and pitfalls. This review explores tractography limitations and how different white matter pathways pose different challenges to fiber tracking methodologies. We summarize the pros and cons of commonly-used methods, aiming to inform how tractography and its related analysis may lead to questionable results. Extending these experiences, we review the clinical utilization of tractography in patients with brain tumors and traumatic brain injury, starting from tensor-based tractography to more advanced methods. We discuss current limitations and highlight novel approaches in the context of these two conditions to inform future tractography developments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.