Evidence map›Paper›PMID 34673220›Full record

ReviewAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2022

Asthma and the social determinants of health.

Torie Grant, Emily Croce, Elizabeth C Matsui

Open access · bronzeAbstract readReview
In one paragraph

Review in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 2 pooled it
33.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 2 syntheses or guidelines pooled it, 202 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
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  10. Review
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  12. Article
  13. Associations between genetic ancestry and allergic outcomes at 10 years among Black children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  14. Observational
  15. Article
  16. Peer racial representation at school, social experiences, and inflammation among Black adolescents.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
  17. Article
  18. Breathing Easy: A Qualitative Analysis of School Nurse and Administrator Perspectives on Stock Inhalers and School-Based Asthma Management.The Journal of school nursing : the official publication of the National Association of School Nurses · 2026
    Article
  19. Article
  20. Observational

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Torie GrantJohns Hopkins University School of Medicine, Baltimore, Maryland.
Emily CroceThe University of Texas at Austin Dell Medical School, Austin, Texas.
Elizabeth C MatsuiThe University of Texas at Austin Dell Medical School, Austin, Texas. Electronic address: elizabeth.matsui@austin.utexas.edu.
The University of Texas at Austin · USJohns Hopkins University · US

Funding

Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUH3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern · 2018 to 2026
$64.8M
The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority childrenR01ES026170 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI KEET, CORINNE, MATSUI, ELIZABETH C. · 2016 to 2025
$6.8M
Environmental Control as Add-on Therapy in Urban Children with AsthmaR01ES023447 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2014 to 2018
$3.4M
Mentoring in Patient-Oriented Research on Asthma and the Indoor EnvironmentK24AI114769 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI MATSUI, ELIZABETH C. · 2015 to 2023
$1.6M
Precision Health Intervention Methodology Training in Self-Management of Multiple Chronic ConditionsT32NR019035 · NINR · UNIVERSITY OF TEXAS AT AUSTIN · PI STUIFBERGEN, ALEXA · 2020 to 2024
$995k
Allergen Exposure Reduction as a Disease-Modifying Strategy in Allergen-Sensitized Children with AsthmaK23AI159144 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRANT, TORIE · 2021 to 2025
$991k
NIAID NIH HHS K23 AI159144NIAID NIH HHS K24 AI114769NIEHS NIH HHS R01 ES023447NIEHS NIH HHS R01 ES026170NIH HHS UH3 OD023282NINR NIH HHS T32 NR019035
6 · The paper itself

Abstract

objectiveTo synthesize the growing body of literature on the role of social determinants of health (SDoH) in asthma and asthma disparities. DATA SOURCES: A pubmed.gov search was performed to identify published literature on SDoH, asthma, asthma disparities, and race and ethnicity. Current asthma statistics of the Centers for Disease Control and Prevention were reviewed. STUDY SELECTIONS: Relevant articles on SDoH, asthma, asthma disparities, and race and ethnicity were reviewed in detail.

resultsBlack and Latinx Americans have a higher asthma prevalence and greater asthma morbidity than White Americans and also bear a disproportionate burden of SDoH. Inequities in SDoH are rooted in structural racism and population-level injustices that affect the socioeconomic status, physical environment, and health care access/quality of Black and Latinx Americans. There is evidence that racial/ethnic inequities in SDoH, such as socioeconomic status, neighborhood environment, housing, environmental exposures, and health care access/quality, contribute to excess burden of asthma prevalence/incidence, morbidity, exacerbations, and abnormal lung function among certain racial/ethnic populations. In addition, Black and Latinx communities experience high levels of long-term stress, which may increase asthma risk through direct effects on the immune system and hypothalamic-pituitary-adrenocortical activation. Long-term stress may also mediate the effects of SDoH on asthma.

conclusionAlthough there is clear evidence linking SDoH to excess asthma risk and implicating SDoH in asthma disparities, the extent to which asthma disparities are explained by inequities in SDoH and the relative contributions of each of these SDoH to asthma disparities remain unclear. This knowledge is needed to effectively develop and test systems-level interventions targeting SDoH, with the ultimate goal of meaningfully reducing racial/ethnic asthma disparities.

Indexed as

AsthmaSocial Determinants of HealthEthnicityHealth Status DisparitiesHumansRacial GroupsSystemic RacismUnited States

Identifiers

PMID34673220
PMCPMC8671352
OpenAlexW3206682544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.