Evidence map›Paper›PMID 34673049›Full record

ArticleThe Journal of allergy and clinical immunology2022

BCG vaccine's off-target effects on allergic, inflammatory, and autoimmune diseases: Worth another shot?

Asimenia Angelidou, Laure F Pittet, Denise Faustman, Nigel Curtis, Ofer Levy

Open access · greenAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of allergy and clinical immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Asimenia AngelidouDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, Mass; Precision Vaccines Program, Division of Infectious Diseases, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
Laure F PittetInfectious Diseases Research Group, Murdoch Children's Research Institute, Royal Children's Hospital Melbourne, Parkville, Australia; Unit of Pediatric Infectious Diseases, Division of General Pediatrics, Department of Pediatrics, Gynecology and Obstetrics, Children's Hospital, University Hospitals of Geneva, Geneva, Switzerland; Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Denise FaustmanDepartment of Pediatrics, Harvard Medical School, Boston, Mass; Department of Immunobiology, Massachusetts General Hospital, Boston, Mass.
Nigel CurtisInfectious Diseases Research Group, Murdoch Children's Research Institute, Royal Children's Hospital Melbourne, Parkville, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Australia.
Ofer LevyPrecision Vaccines Program, Division of Infectious Diseases, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Mass. Electronic address: ofer.levy@childrens.harvard.edu.
Murdoch Children's Research Institute · AUHarvard University · USMassachusetts General Hospital · USMassachusetts Institute of Technology · US

Funding

Transcriptomics to define biomarkers of neonatal vaccine immunogenicityU19AI118608 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI LEVY, OFER · 2017 to 2021
$24.7M
NIAID NIH HHS U19 AI118608
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Autoimmune DiseasesBCG VaccineHumansHypersensitivityInflammationRandomized Controlled Trials as TopicBCG VaccineAllergyautoimmunityBacille Calmette-Guérin vaccineBCG vaccineinflammatory diseases

Identifiers

PMID34673049
PMCPMC11688639
OpenAlexW3205205939

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.