ArticleJournal of the Royal Society of Medicine2022
Association between multimorbidity and mortality in a cohort of patients admitted to hospital with COVID-19 in Scotland.
Article in Journal of the Royal Society of Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- COVID-19-related morbidity and mortality in people with multiple long-term conditions: a systematic review and meta-analysis of over 4 million people.Journal of the Royal Society of Medicine · 2024Pooled it
- Multimorbidity and frailty are associated with poorer SARS-CoV-2-related outcomes: systematic review of population-based studies.Aging clinical and experimental research · 2024Pooled it
- Trial
- Intellectual and Physical Disability and Risk of COVID-19 Infection, Hospitalisation, and Mortality: A National Cohort of 3.7 Million Adults in Scotland.Journal of epidemiology and global health · 2026Article
- Impact of Risk Factor Combinations on Severe COVID-19 Outcomes Among Outpatients.Infectious diseases and therapy · 2026Article
- The Multimorbidity Knowledge Domain: A Bibliometric Analysis of Web of Science Literature from 2004 to 2024.Healthcare (Basel, Switzerland) · 2025Article
- Early detection of cytokine storm and IgG levels to predict and prevent severe COVID-19 infection.Journal of family medicine and primary care · 2025Article
- Relationship between multimorbidity, SARS-COV-2 infection and long COVID: a cross-sectional population-based French survey.BMC medicine · 2025Article
- A Digital Tool for Clinical Evidence-Driven Guideline Development by Studying Properties of Trial Eligible and Ineligible Populations: Development and Usability Study.Journal of medical Internet research · 2025Article
- Creating a Modified Version of the Cambridge Multimorbidity Score to Predict Mortality in People Older Than 16 Years: Model Development and Validation.Journal of medical Internet research · 2024Article
- Comprehensive Review of COVID-19: Epidemiology, Pathogenesis, Advancement in Diagnostic and Detection Techniques, and Post-Pandemic Treatment Strategies.International journal of molecular sciences · 2024Review
- Rural-urban Differences in Long-term Mortality and Readmission Following COVID-19 Hospitalization, 2020 to 2023.Open forum infectious diseases · 2024Article
- Article
- Article
- Article
- Diabetes and Multiple Long-term Conditions: A Review of Our Current Global Health Challenge.Diabetes care · 2023Review
- Maternal multimorbidity and preterm birth in Scotland: an observational record-linkage study.BMC medicine · 2023Observational
- Review
- Article
- Cognitive Decline Before and During COVID-19 Pandemic Among Older People With Multimorbidity: A Longitudinal Study.Journal of the American Medical Directors Association · 2023Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
objectivesWe investigated the association between multimorbidity among patients hospitalised with COVID-19 and their subsequent risk of mortality. We also explored the interaction between the presence of multimorbidity and the requirement for an individual to shield due to the presence of specific conditions and its association with mortality.
designWe created a cohort of patients hospitalised in Scotland due to COVID-19 during the first wave (between 28 February 2020 and 22 September 2020) of the pandemic. We identified the level of multimorbidity for the patient on admission and used logistic regression to analyse the association between multimorbidity and risk of mortality among patients hospitalised with COVID-19.
settingScotland, UK.
participantsPatients hospitalised due to COVID-19.
main outcome measuresMortality as recorded on National Records of Scotland death certificate and being coded for COVID-19 on the death certificate or death within 28 days of a positive COVID-19 test.
resultsAlmost 58% of patients admitted to the hospital due to COVID-19 had multimorbidity. Adjusting for confounding factors of age, sex, social class and presence in the shielding group, multimorbidity was significantly associated with mortality (adjusted odds ratio 1.48, 95%CI 1.26-1.75). The presence of multimorbidity and presence in the shielding patients list were independently associated with mortality but there was no multiplicative effect of having both (adjusted odds ratio 0.91, 95%CI 0.64-1.29).
conclusionsMultimorbidity is an independent risk factor of mortality among individuals who were hospitalised due to COVID-19. Individuals with multimorbidity could be prioritised when making preventive policies, for example, by expanding shielding advice to this group and prioritising them for vaccination.
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