Evidence map›Paper›PMID 34672767›Full record

Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2021

On the implication of dietary nitrate supplementation for the hemodynamic and fatigue response to cycling exercise.

Taylor S Thurston, Joshua C Weavil, Thomas J Hureau, Jayson R Gifford, Vincent P Georgescu, Hsuan-Yu Wan, D Taylor La Salle, Russell S Richardson, Markus Amann

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Hypertension restricts leg blood flow and aggravates neuromuscular fatigue during human locomotion in males.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Taylor S ThurstonDepartment of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah.ORCID 0000-0002-4536-3054
Joshua C WeavilGeriatric Research, Education, and Clinical Center, Salt Lake City, Utah.ORCID 0000-0002-2032-8498
Thomas J HureauDepartment of Medicine, University of Utah, Salt Lake City, Utah.ORCID 0000-0002-6993-5723
Jayson R GiffordDepartment of Medicine, University of Utah, Salt Lake City, Utah.
Vincent P GeorgescuDepartment of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah.
Hsuan-Yu WanDepartment of Anesthesiology, University of Utah, Salt Lake City, Utah.ORCID 0000-0001-8853-8451
D Taylor La SalleDepartment of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah.
Russell S RichardsonDepartment of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah.
Markus AmannDepartment of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah.

Funding

Role of Sensory Neurons in Human Cardiovascular DiseaseR01HL116579 · NHLBI · UNIVERSITY OF UTAH · PI AMANN, MARKUS · 2013 to 2021
$3.4M
Cardiovasomobility Research Training ProgramT32HL139451 · NHLBI · UNIVERSITY OF UTAH · PI SUPIANO, MARK A, WRAY, D. WALTER · 2018 to 2022
$1.4M
Work of Breathing and Oxidative Stress in COPD: Impact on Blood Flow and FatigueR00HL103786 · NHLBI · UNIVERSITY OF UTAH · PI AMANN, MARKUS · 2013 to 2015
$738k
Respiratory muscle work and oxidative stress in COPD: impact on leg blood flow anK99HL103786 · NHLBI · UNIVERSITY OF UTAH · PI AMANN, MARKUS · 2010 to 2011
$161k
NHLBI NIH HHS HL-103786NHLBI NIH HHS HL457 116579NHLBI NIH HHS K99 HL103786NHLBI NIH HHS R00 HL103786NHLBI NIH HHS T32 HL139451
6 · The paper itself

Abstract

This study investigated the impact of dietary nitrate supplementation on peripheral hemodynamics, the development of neuromuscular fatigue, and time to task failure during cycling exercise. Eleven recreationally active male participants (27 ± 5 yr, V̇o

Indexed as

Beta vulgarisNitratesCross-Over StudiesDietary SupplementsDouble-Blind MethodExerciseHemodynamicsHumansMaleMuscle FatigueMuscle, SkeletalNitratesbeetroot juiceblood flowdietary nitrateneuromuscular fatiguenitric oxide

Identifiers

PMID34672767
PMCPMC8714979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.