Evidence map›Paper›PMID 34672646›Full record

ArticleCultural diversity & ethnic minority psychology2022

Chronic stress, autonomic dysregulation and prospective drug use among African American emerging adults.

Lucia Cavanagh, Ezemenari M Obasi

Open access · hybridAbstract read
In one paragraph

Article in Cultural diversity & ethnic minority psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Relationship intervention moderates the association between substance use and biological aging among Black adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Trial
  3. Article
  4. Parasympathetic decreases immediately following self-reported cannabis smoking among adults living with cannabis use disorder.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lucia CavanaghDepartment of Psychological, Health and Learning Sciences, Hwemudua Addictions & Health Disparities Laboratory (HAHDL), University of Houston.ORCID 0000-0002-4109-8169
Ezemenari M ObasiDepartment of Psychological, Health and Learning Sciences, Hwemudua Addictions & Health Disparities Laboratory (HAHDL), University of Houston.ORCID 0000-0003-2142-952X
Department of Health · TW

Funding

Testing a Digital Therapeutic for Smoking Cessation among Hispanic Persons who SmokeU54MD015946 · NIMHD · UNIVERSITY OF HOUSTON · PI Fatima Aziz Merchant · 2020 to 2026
$22.0M
Stress and Drug Use Vulnerability in the African American CommunityR01DA034739 · NIDA · UNIVERSITY OF HOUSTON · PI OBASI, EZEMENARI M · 2013 to 2017
$2.5M
NIDA NIH HHS R01 DA034739NIMHD NIH HHS U54 MD015946
6 · The paper itself

Abstract

objectiveChronic stress is associated with increased vulnerability to drug use and may contribute to drug-related health disparities in the African American community. The underlying physiological mechanisms by which chronic stress confers this increased risk remain unclear. The present study aimed to characterize the impact of chronic and race-related stress exposure on regulatory mechanisms of the autonomic nervous system (ANS) in response to acute stress, to examine John Henryism as potential moderator of this relationship, and to investigate the association between ANS reactivity and subsequent drug use among a sample of African American emerging adults (18-25 years old) in the Southern United States (U.S.).

methodParticipants (

resultsRace-related stress was associated with greater SCL reactivity. John Henryism moderated the relationship between chronic stress exposure and HRV reactivity. SCL reactivity was associated with higher rates of alcohol and marijuana use at 90-day follow-up. HRV reactivity was associated with tobacco use at 90-day follow-up.

conclusionsChronic stress exposure and active coping may interact to affect regulatory mechanisms of the ANS. ANS (dys)regulation may be an important endophenotype for increasing drug use vulnerability among African American emerging adults. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Pharmaceutical PreparationsSubstance-Related DisordersAdaptation, PsychologicalAdolescentAdultBlack or African AmericanHumansRetrospective StudiesUnited StatesYoung AdultPharmaceutical Preparations

Identifiers

PMID34672646
PMCPMC9531769
OpenAlexW3206975391

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.