Evidence map›Paper›PMID 34672436›Full record

SynthesisPediatric pulmonology2022

Pediatric asthma control during the COVID-19 pandemic: A systematic review and meta-analysis.

Ze Yang, Xiang Wang, Xi-Gang Wan, Meng-Lei Wang, Zong-Hua Qiu, Jia-Li Chen, Man-Hao Shi, Shi-Yi Zhang, Yong-Liang Xia

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Incidence of New Asthma and Asthma Exacerbation Pre- and Post-COVID-19 Pandemic in the United States.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
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  11. Multilevel facilitators of pediatric asthma outcomes: The role of caregiver self-efficacy.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ze YangThe First Clinical Medical College of Zhejiang Traditional Chinese Medical University, Hangzhou, China.
Xiang WangThe First Clinical Medical College of Zhejiang Traditional Chinese Medical University, Hangzhou, China.
Xi-Gang WanThe First Clinical Medical College of Zhejiang Traditional Chinese Medical University, Hangzhou, China.
Meng-Lei WangThe Third Clinical Medical College of Zhejiang Traditional Chinese Medical University, Hangzhou, China.
Zong-Hua QiuThe First Clinical Medical College of Zhejiang Traditional Chinese Medical University, Hangzhou, China.
Jia-Li ChenThe First Clinical Medical College of Zhejiang Traditional Chinese Medical University, Hangzhou, China.
Man-Hao ShiThe First Clinical Medical College of Zhejiang Traditional Chinese Medical University, Hangzhou, China.
Shi-Yi ZhangThe First Clinical Medical College of Zhejiang Traditional Chinese Medical University, Hangzhou, China.
Yong-Liang XiaDepartment of Internal Traditional Chinese Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.ORCID 0000-0002-4385-5856
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the onset of the coronavirus disease 2019 (COVID-19) pandemic, many experts expected that asthma-associated morbidity because of severe acute respiratory syndrome coronavirus 2 infection would dramatically increase. However, some studies suggested that there was no apparent increasing in asthma-related morbidity in children with asthma, it is even possible children may have improved outcomes. To understand the relationship between the COVID-19 pandemic and asthma outcomes, we performed this article.

methodsWe searched PubMed, Embase, and Cochrane Library to find literature from December 2019 to June 2021 related to COVID-19 and children's asthma control, among which results such as abstracts, comments, letters, reviews, and case reports were excluded. The level of asthma control during the COVID-19 pandemic was synthesized and discussed by outcomes of asthma exacerbation, emergency room visit, asthma admission, and childhood asthma control test (c-ACT).

resultsA total of 22,159 subjects were included in 10 studies. Random effect model was used to account for the data. Compared with the same period before the COVID-19 pandemic, asthma exacerbation reduced (odds ratio [OR] = 0.26, 95% confidence interval [CI] = [0.14-0.48], Z = 4.32, p < 0.0001), the odds of emergency room visit decreased as well (OR = 0.11, 95% CI = [0.04-0.26], Z = 4.98, p < 0.00001). The outcome of asthma admission showed no significant difference (OR = 0.84, 95% CI = [0.32-2.20], Z = 0.36, p = 0.72). The outcome of c-ACT scores were not analyzed because of the different manifestations used. Overall, c-ACT scores reduced during the pandemic.

conclusionCompared to the same period before the COVID-19 pandemic, the level of asthma control has been significantly improved. We need to understand the exact factors leading to these improvements and find methods to sustain it.

Indexed as

AsthmaCOVID-19ChildHospitalizationHumansPandemicsSARS-CoV-2asthma controlchildrenCOVID-19systematic review and meta-analysis

Identifiers

PMID34672436
PMCPMC8662014
OpenAlexW3207884321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.