Evidence map›Paper›PMID 34672186›Full record

ArticleJBRA assisted reproduction2022

Advantages and disadvantages of using Carbon Nanostructures in Reproductive Medicine: two sides of the same coin.

Hadi Zare-Zardini, Nooshin Hatamizadeh, Navid Haddadzadegan, Hossein Soltaninejad, Mojgan Karimi-Zarchi

Open access · bronzeAbstract read
In one paragraph

Article in JBRA assisted reproduction, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
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  5. MXene and prostate cancer: is there promising news?Nanomedicine (London, England) · 2025
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  6. Is Emerging Nanomedicine a Friend or Foe to Germ Cells?International journal of nanomedicine · 2025
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hadi Zare-ZardiniHematology and Oncology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Nooshin HatamizadehDepartment of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Navid HaddadzadeganDepartment of Anesthesiology and Critical Care, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Hossein SoltaninejadDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Mojgan Karimi-ZarchiDepartment of Gynecology Oncology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Shahid Sadoughi University of Medical Sciences and Health Services · IRMofid University · IRTarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon nanostructures are important nanomaterial with interesting physical and chemical properties. These nanostructures have been assessed for application in different fields of medicine, such as cancer detection and treatment, Parkinson disease, reproductive medicine, etc. This nanomaterial can be used in reproductive medicine as a drug delivery system, antifungal, antiviral, and antibacterial agent, condom-coating agent, enhancer of sperm fertilizing ability, ectopic pregnancy treatment, trophoblastic diseases, endometriosis, uterine fibroids, and Assisted Reproduction Techniques (ART) improvement. The other side of this coin involves various side effects of carbon nanostructures, especially negative effects on reproductive systems. All carbon nanostructures showed toxicity on the reproductive system by producing reactive oxygen species and oxidative stress. Less attention has been given to the unique properties of carbon nanostructures, except for their practical attractiveness, the other side of this coin, namely the risks and side effects of these compounds - especially in the case of a reproductive system that supports the survival and health of future generations. Therefore, we suggest paying particular attention to the negative aspects of the increasing use of carbon nanostructures.

Indexed as

NanostructuresReproductive MedicineCarbonFemaleHumansOxidative StressPregnancyReproductive Techniques, AssistedCarbonattentioncarbon nanostructuresreproductive medicineside effects

Identifiers

PMID34672186
PMCPMC8769193
OpenAlexW3206546212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.