Evidence map›Paper›PMID 34672127›Full record

ArticleCancer reports (Hoboken, N.J.)2022

Perspectives of pediatric oncologists and palliative care physicians on the therapeutic use of cannabis in children with cancer.

Sapna Oberoi, Jennifer L P Protudjer, Adam Rapoport, Shahrad R Rassekh, Bruce Crooks, Harold Siden, Kathleen Decker, Prasanna Ananth, Stacy Chapman, Lynda G Balneaves and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Sapna OberoiDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.ORCID 0000-0002-6071-0042
Jennifer L P ProtudjerDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.
Adam RapoportPaediatric Advanced Care Team, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-5090-8987
Shahrad R RassekhDivision of Oncology/Hematology/BMT, Department of Pediatrics, University of British Columbia, Vancouver, Canada.ORCID 0000-0001-8005-2641
Bruce CrooksPediatric Hematology/Oncology & Medical Education, IWK Health Centre, Halifax, Canada.
Harold SidenDepartment of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Kathleen DeckerDepartment of Community Health Sciences, University of Manitoba, Winnipeg, Canada.
Prasanna AnanthSection of Pediatric Hematology/Oncology, Department of Pediatrics, Yale School of Medicine.ORCID 0000-0002-5614-7445
Stacy ChapmanDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.
Lynda G BalneavesCollege of Nursing, University of Manitoba, Winnipeg, Canada.
Magimairajan Issai VananDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.ORCID 0000-0003-2015-0615
Lauren E KellyDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada.
CancerCare Manitoba · CAChildren's Hospital Research Institute of Manitoba · CAUniversity of British Columbia · CAUniversity of Manitoba · CAIzaak Walton Killam Health Centre · CAUniversity of Toronto · CAYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
CIHR 707031NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

backgroundChildren with cancer are increasingly using cannabis therapeutically.

aimThe purpose of this study was to determine the perspectives and practices of pediatric oncologists and palliative care physicians regarding the use of cannabis for medical purposes among children with cancer.

methodsA self-administered, voluntary, cross-sectional, deidentified online survey was sent to all pediatric oncologists and palliative care physicians in Canada between June and August 2020. Survey domains included education, knowledge, and concerns about cannabis, views on its effectiveness, and the importance of cannabis-related research. Data were analyzed using descriptive statistics.

resultsIn total, 122/259 (47.1%) physicians completed the survey. Although 62.2% of the physicians completed some form of training about medical cannabis, nearly all (95.8%) desired to know more about the dosing, side effects, and safety of cannabis. Physicians identified a potential role of cannabis in the management of nausea and vomiting (85.7%), chronic pain (72.3%), cachexia/poor appetite (67.2%), and anxiety or depression (42.9%). Only four (0.3%) physicians recognized cannabis to be potentially useful as an anticancer agent. Nearly all physicians reported that cannabis-related research for symptom relief is essential (91.5%) in pediatric oncology, whereas 51.7% expressed that future studies are necessary to determine the anticancer effects of cannabis.

conclusionsOur findings indicate that most pediatric oncologists and palliative care physicians recognize a potential role for cannabis in symptom control in children with cancer. Well-conducted studies are required to create evidence for cannabis use and promote shared decision making with pediatric oncology patients and their caregivers.

Indexed as

CannabisNeoplasmsOncologistsPhysiciansChildCross-Sectional StudiesHumansPalliative Carecancercannabidiolcannabispediatricssymptom controltetrahydrocannabinol

Identifiers

PMID34672127
PMCPMC9458513
OpenAlexW3207706269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.