ArticleAndrologia2022
COVID-19 vaccination is associated with a decreased risk of orchitis and/or epididymitis in men.
Article in Andrologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Systematic literature review and meta-analysis on the reproductive effects of micro- pollutants in humans and animals.Frontiers in toxicology · 2025Pooled it
- Effects of SARS-CoV-2 Vaccines on Sperm Quality: Systematic Review.JMIR public health and surveillance · 2023Pooled it
- Effect of COVID-19 vaccination on semen parameters: A systematic review and meta-analysis.Journal of medical virology · 2023Pooled it
- Pooled it
- Endocrine system after 2 years of COVID-19 vaccines: A narrative review of the literature.Frontiers in endocrinology · 2022Pooled it
- Correlation between viral infections in male semen and infertility: a literature review.Virology journal · 2024Review
- Review
- SARS-CoV-2 and male infertility: from short- to long-term impacts.Journal of endocrinological investigation · 2023Review
- COVID-19 and Male Infertility: Is There a Role for Antioxidants?Antioxidants (Basel, Switzerland) · 2023Review
- Updates in the pathophysiology of COVID-19 infection in male reproductive and sexual health: a literature review.Frontiers in endocrinology · 2023Review
- The Effect of Long COVID-19 Infection and Vaccination on Male Fertility; A Narrative Review.Vaccines · 2022Review
- Investigate the effect of COVID-19 inactivated vaccine on sperm parameters and embryo quality in in vitro fertilization.Andrologia · 2022Article
- Linking COVID-19 vaccine and male infertility - not on fertile ground.BJU international · 2022Article
- Corona and Reproduction, or Why the Corona Vaccination Does Not Result in Infertility.Geburtshilfe und Frauenheilkunde · 2022Article
- COVID-19 vaccination is associated with a decreased risk of orchitis and/or epididymitis in men.Andrologia · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vaccine hesitancy is a major public health obstacle to fighting the ongoing COVID-19 epidemic. Due to studies that show COVID-19 infection can affect sperm parameters and lead to orchitis, the public are concerned about the effect of the COVID vaccines on male reproduction. In this study, we investigated the association between COVID-19 vaccination and risk of developing orchitis and/or epididymitis outcomes in a cohort of men using a large, US-based, electronic health record database. After balancing for confounding variables, we found that receiving at least 1 COVID-19 vaccine is associated with a decreased risk of developing orchitis and/or epididymitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.