Evidence map›Paper›PMID 34671911›Full record

ArticleSleep & breathing = Schlaf & Atmung2022

Sleep-disordered breathing patterns in hospitalized patients with acute heart failure across the entire spectrum of ejection fraction.

Sérgio Maltês, Gonçalo J L Cunha, Bruno M L Rocha, Renato Guerreiro, Joana Duarte, Rui Morais, Célia Henriques, Catarina Rodrigues, Inês Araújo, Cândida Fonseca

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sérgio MaltêsHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal. sergiomaltes@campus.ul.pt.
Gonçalo J L CunhaHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Bruno M L RochaHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Renato GuerreiroHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Joana DuarteHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Rui MoraisHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Célia HenriquesHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Catarina RodriguesHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Inês AraújoHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Cândida FonsecaHeart Failure Clinic, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ociental, Lisbon, Portugal.
Centro Hospitalar de Lisboa Ocidental · PTUniversidade Nova de Lisboa · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSleep-disordered breathing (SDB) is prevalent in heart failure (HF). Yet, scarce data exist on sleep-patterns in acute HF and differences in specific subgroups. Our goal was to assess SDB prevalence in hospitalized patients with decompensated HF across the entire spectrum of left ventricle ejection fraction (LVEF).

methodsSingle-center retrospective study enrolling patients admitted for acute HF between 2013 and 2018. All patients were screened for SDB with an ApneaLink™ Plus device before discharge while euvolemic and receiving oral therapy. Those with a sleep study time < 3 h were excluded. HF with reduced, moderately reduced, and preserved LVEF (HFrEF, HFmrEF, and HFpEF) was defined by a LVEF < 40%, 40-49%, and ≥ 50%, respectively. SDB was defined by an apnea-hypopnea index (AHI) ≥ 5/h.

resultsOverall, 221 patients were included (mean age 75 ± 11 years). Seventy-two (33%) had HFrEF, 26 (11%) HFmrEF, and 123 (56%) HFpEF. In total, 176 (80%) met the criteria for mild SDB, while 59% and 38% had an AHI ≥ 15/h or ≥ 30/h, respectively. SDB prevalence was high and similar between HFrEF, HFmrEF, and HFpEF. Yet, SDB was often more severe in HFrEF when compared to HFpEF. HFmrEF had intermediate characteristics, with an AHI closer to HFrEF.

conclusionIn a cohort of patients admitted for acute HF, SDB was highly prevalent in all subgroups, including HFmrEF. The pervasiveness and severity of SDB was particularly noted in HFrEF. These findings suggest that routine SDB screening may be warranted following acute HF.

Indexed as

Heart FailureSleep Apnea SyndromesAgedAged, 80 and overHumansMiddle AgedPrognosisRetrospective StudiesStroke VolumeVentricular Function, LeftHeart failureLeft ventricle ejection fractionPortable sleep monitorSleep apneaSleep-disordered breathing

Identifiers

PMID34671911
OpenAlexW3206564139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.