Evidence map›Paper›PMID 34671819›Full record

ArticleEuropean journal of clinical pharmacology2022

Feasibility and usability of a mobile health tool on anticoagulation management for patients with atrial fibrillation: a pilot study.

Chi Zhang, Mang-Mang Pan, Na Wang, Wei-Wei Wang, Zheng Li, Zhi-Chun Gu, Hou-Wen Lin

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Article in European journal of clinical pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Chi Zhang *Department of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Mang-Mang Pan *Department of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Na WangDepartment of Pharmacy, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Wei-Wei WangDepartment of S/4HANA Research & Development, SAP (China) Co., Ltd, Shanghai, 201203, China.
Zheng LiDepartment of Cardiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Zhi-Chun GuDepartment of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China. guzhichun213@163.com.ORCID http://orcid.org/0000-0002-1245-9690
Hou-Wen LinDepartment of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Shanghai Jiao Tong University · CNTongji University · CNDalian Medical University · CNRenji Hospital · CN

Funding

clinical pharmacy innovation research institute of shanghai jiao tong university school of medicine CXYJY2019ZD001cultivation fund of clinical research of renji hospital PY2018-III-06research funds of shanghai health and family planning commission 20184Y0022shanghai "rising stars of medical talent" youth development program - youth medical talents - clinical pharmacist program SHWJRS (2019) 072shanghai "rising stars of medical talent" youth development program - youth medical talents - clinical pharmacist program SHWRS (2020) 087wu jieping medical foundation 320.6750.2020-04-30
6 · The paper itself

Abstract

purposeAppropriate prescription of oral anticoagulants (OACs) and good patient adherence are essential to ensure optimal anticoagulation in patients with atrial fibrillation (AF). The aim of this study is to develop a mobile health tool to aid both clinicians and patients with AF in anticoagulation therapy.

methodsIn this study, a novel anticoagulation management model integrating decision support and patient follow-up, the I-Anticoagulation, was developed based on a WeChat Mini Program. With this tool, the risks of stroke and bleeding in AF patients can automatically be calculated according to their characteristics. Anticoagulation regimens were recommended based on a trade-off analysis that balances stroke and bleeding risks according to recent clinical guidelines. A shared decision can be made with full communication between medical professionals and patients. Moreover, follow-up was also conducted using I-Anticoagulation.

resultsA total of 120 AF patients receiving anticoagulants (40 received warfarin and 80 received non-vitamin K antagonist oral anticoagulants [NOACs]) were included in the pilot study. The incidence of thromboembolic events was 2.5% and 1.3%, and the rates of bleeding events were 22.5% and 13.8% in the warfarin and NOAC groups, respectively. Generally, self-reported adherence was high, and the satisfaction with anticoagulation was good in all patients with AF.

conclusionOverall, the anticoagulation management model developed in this study could be involved in the full process of anticoagulation therapy in AF patients to improve rationality, adherence, and satisfaction in both medical professionals and patients. However, the usability, feasibility, and acceptability of the I-Anticoagulant-based anticoagulation management model need to be further assessed through well-designed random clinical trials.

Indexed as

AgedAged, 80 and overAge FactorsAnticoagulantsAtrial FibrillationCommunicationComorbidityDecision Support Systems, ClinicalFeasibility StudiesFemaleHealth BehaviorHemorrhageHumansMaleMiddle AgedPatient ParticipationAnticoagulantsAnticoagulationAtrial fibrillationClinical decision supportMobile health technologyRivaroxabanWarfarin

Identifiers

PMID34671819
OpenAlexW3207157161

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.