Evidence map›Paper›PMID 34671728›Full record

ArticleJAC-antimicrobial resistance2021

Frequency of occurrence and antimicrobial susceptibility of bacteria isolated from respiratory samples of patients hospitalized with pneumonia in Western Europe, Eastern Europe and the USA: results from the SENTRY Antimicrobial Surveillance Program (2016-19).

Helio S Sader, Jennifer M Streit, Cecilia G Carvalhaes, Michael D Huband, Dee Shortridge, Rodrigo E Mendes, Mariana Castanheira

Registry-linked trialAbstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06738771 (Antimicrobial Therapy for Infections Due to Pseudomonas Aeruginosa With Difficult-to-treat Resistance), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06738771 recruitingnot on this mapstarted 2025, after this paper: background citation

Antimicrobial Therapy for Infections Due to Pseudomonas Aeruginosa With Difficult-to-treat Resistance: a Real-world, Prospective, Multicenter Cohort Study

TypeobservationalSponsorCentre Hospitalier Régional d'OrléansRan2025 to 2027Enrolled600ConditionsPseudomonas Infections, Pseudomonas Aeruginosa, Prognosis, Drug Resistance, Multiple, Bacterial
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Comparison ofInfection and immunity · 2026
    Article
  4. Article
  5. From Environmental Organism to Nosocomial Threat:Antibiotics (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Comparison ofbioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Observational
  12. Novel Antibiotics and Emerging Resistance: Infectious diseases & clinical microbiology · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Infection characteristics amongbioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Helio S SaderJMI Laboratories, North Liberty, IA 52317, USA.
Jennifer M StreitJMI Laboratories, North Liberty, IA 52317, USA.
Cecilia G CarvalhaesJMI Laboratories, North Liberty, IA 52317, USA.ORCID https://orcid.org/0000-0002-2734-3754
Michael D HubandJMI Laboratories, North Liberty, IA 52317, USA.
Dee ShortridgeJMI Laboratories, North Liberty, IA 52317, USA.
Rodrigo E MendesJMI Laboratories, North Liberty, IA 52317, USA.
Mariana CastanheiraJMI Laboratories, North Liberty, IA 52317, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe SENTRY Antimicrobial Surveillance Program monitors the frequency of occurrence and antimicrobial susceptibility of organisms from various infection types worldwide.

objectivesTo evaluate the SENTRY programme results for organisms isolated from respiratory samples of patients hospitalized with probable pneumonia.

methodsA total of 28 918 bacterial isolates were consecutively collected (one per patient) in 2016-19 from 121 medical centres located in western Europe (W-EU;

resultsGram-negative bacilli (GNB) represented 76.3%, 88.6% and 69.1% of organisms; non-fermentative (NF) GNB accounted for 26.9%, 51.8% and 34.6% of organisms in W-EU, E-EU and USA, respectively.

conclusionsRank order and antimicrobial susceptibility of bacteria isolated from patients with pneumonia widely varied by geography. MDR NF-GNB represented an important cause of pneumonia.

Identifiers

PMID34671728
PMCPMC8522161

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.