Evidence map›Paper›PMID 34671659›Full record

ArticleFrontiers in veterinary science2021

Directed Expression of Tracheal Antimicrobial Peptide as a Treatment for Bovine-Associated

Zhipeng Zhang, Daijie Chen, Xubin Lu, Ruifeng Zhao, Zhi Chen, Mingxun Li, Tianle Xu, Yongjiang Mao, Yi Yang, Zhangping Yang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zhipeng ZhangCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Daijie ChenCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Xubin LuCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Ruifeng ZhaoCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Zhi ChenCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Mingxun LiCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Tianle XuCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Yongjiang MaoCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Yi YangJoint International Research Laboratory of Agriculture & Agri-Product Safety, Ministry of Education, Yangzhou University, Yangzhou, China.
Zhangping YangCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine mastitis is perplexing the dairy industry since the initiation of intensive dairy farming, which has caused a reduction in the productivity of cows and an escalation in costs. The use of antibiotics causes a series of problems, especially the formation of bacterial antimicrobial resistance. However, there are limited antibiotic-free therapeutic strategies that can effectively relieve bacterial infection of bovine mammary glands. Hence, in this study, we constructed a mammary gland tissue-specific expression vector carrying the antimicrobial peptide of bovine-derived tracheal antimicrobial peptide (

Indexed as

antibiotic alternativesbovine mastitismice modelplasmidS. aureusTAP

Identifiers

PMID34671659
PMCPMC8520960
OpenAlexW3203738443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.