ArticleFrontiers in nutrition2021
Antioxidant Vitamins and Carotenoids Intake and the Association With Poor Semen Quality: A Cross-Sectional Analysis of Men Referring to an Italian Fertility Clinic.
Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Causal Associations of Circulating Micronutrients With the Risk of Infertility: A Mendelian Randomization Study.Food science & nutrition · 2025Article
- Review
- Dietary fat and fatty acid consumptions and the odds of asthenozoospermia: a case-control study in China.Human reproduction open · 2023Article
- Association between dietary total antioxidant capacity and semen quality among men attending an infertility clinic: a cross-sectional study.Human reproduction open · 2023Article
- Association of dietary total antioxidant capacity, alternative healthy eating index, and dietary inflammatory index with semen quality in men seeking infertility treatment.Frontiers in nutrition · 2023Article
- Phytochemical consumption and the risk of teratozoospermia: findings from a hospital-based case-control study in China.Human reproduction open · 2023Article
- Diet and Male Fertility: The Impact of Nutrients and Antioxidants on Sperm Energetic Metabolism.International journal of molecular sciences · 2022Review
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Authors and funding
10 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Several studies suggested that male's diet affects fertility. This cross-sectional analysis from a prospective cohort study aims to explore the relation between antioxidants intake and sperm parameters in sub-fertile couples referring to a Fertility center. Socio-demographic characteristics, health history, lifestyle habits, and diet information were obtained. A semen sample was analyzed to proceed with assisted reproduction. Three hundred and twenty-three men were enrolled: 19.1% had semen volume (SV) < 1.5 mL, 31.4% sperm concentration (SC) < 15.0 mil/mL, 26.8% sperm motility < 32%, and 33.0% had total sperm count (TSC) < 39.0 mil. Higher levels of α-carotene were associated to lower risk of low SC [4th vs. 1st quartile, adjusted OR (aOR) 0.43, 95% CI 0.20-0.91) and low TSC (aOR 0.46, 95% CI 0.22-0.95). Higher intake of β-carotene was inversely associated with risk of low TSC. Lycopene intake was associated with higher risk for these conditions (aOR 2.46, 95%CI 1.01-5.98, SC), and (aOR 3.11, 95%CI 1.29-7.50, TSC). Risk of low semen volume was lower in men with higher level of vitamin D intake (aOR 0.25, 95%CI 0.09-0.66)]. Further research, especially, well-designed randomized clinical trials (RCT), is needed to understand how diet modifications may have a role in modulating male fertility and fecundability.
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