ArticleApplied sciences (Basel, Switzerland)2021
Numerical and experimental investigations on vocal fold approximation in healthy and simulated unilateral vocal fold paralysis.
Article in Applied sciences (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 15 citations in OpenAlex.
- Comprehensive Numerical and Experimental Investigations on Endolaryngeal Mobilization.Laryngoscope investigative otolaryngology · 2026Article
- Discovering the Effects of Superior-Surface Vocal Fold Lesions via Fluid-Structure Interaction Analysis.Bioengineering (Basel, Switzerland) · 2025Article
- An Integrated Experimental-Computational Study of Vocal Fold Vibration in Type I Thyroplasty.Journal of biomechanical engineering · 2024Article
- Subject-Specific Modeling of Implant Placement for Type I Thyroplasty Surgery.Annals of biomedical engineering · 2023Article
- Effects of implant and vocal fold stiffness on voice production after medialization laryngoplasty in an MRI-based vocal fold model.Journal of biomechanics · 2023Article
- 3D VOSNet: Segmentation of endoscopic images of the larynx with subsequent generation of indicators.Heliyon · 2023Article
- Towards modeling of phonation and its recovery in unilateral vocal fold paralysis by fluid-structure interaction.BioImpacts : BI · 2023Article
- Segmentation of Glottal Images from High-Speed Videoendoscopy Optimized by Synchronous Acoustic Recordings.Sensors (Basel, Switzerland) · 2022Article
- A twinning bare bones particle swarm optimization algorithm.PloS one · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
We have developed a novel surgical/computational model for the investigation of unilateral vocal fold paralysis (UVFP) which will be used to inform future in silico approaches to improve surgical outcomes in type I thyroplasty. Healthy phonation (HP) was achieved using cricothyroid suture approximation on both sides of the larynx to generate symmetrical vocal fold closure. Following high-speed videoendoscopy (HSV) capture, sutures on the right side of the larynx were removed, partially releasing tension unilaterally and generating asymmetric vocal fold closure characteristic of UVFP (sUVFP condition). HSV revealed symmetric vibration in HP, while in sUVFP the sutured side demonstrated a higher frequency (10 - 11%). For the computational model, ex vivo magnetic resonance imaging (MRI) scans were captured at three configurations: non-approximated (NA), HP, and sUVFP. A finite-element method (FEM) model was built, in which cartilage displacements from the MRI images were used to prescribe the adduction and the vocal fold deformation was simulated before the eigenmode calculation. The results showed that the frequency comparison between the two sides were consistent with observations from HSV. This alignment between the surgical and computational models supports the future application of these methods for the investigation of treatment for UVFP.
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