Evidence map›Paper›PMID 34671436›Full record

ArticleOxidative medicine and cellular longevity2021

Ghrelin Alleviates Endoplasmic Reticulum Stress in MC3T3E1 Cells by Inhibiting AMPK Phosphorylation.

Xue Lv, Qianping Zhang, Bingfei Cheng, Ying Xin, Jun Wang, Juanjuan Li, Chengqian Li, Nailong Yang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xue LvDepartment of Pathology and Pathophysiology, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310058, China.ORCID https://orcid.org/0000-0002-0275-7360
Qianping ZhangDepartment of Endocrinology and Metabolism, Dezhou Municipal Hospital, Dezhou, Shandong 253000, China.ORCID https://orcid.org/0000-0002-4742-7760
Bingfei ChengDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266555, China.ORCID https://orcid.org/0000-0002-4726-7752
Ying XinDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266555, China.ORCID https://orcid.org/0000-0003-2910-9192
Jun WangDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266555, China.ORCID https://orcid.org/0000-0002-9281-943X
Juanjuan LiDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266555, China.ORCID https://orcid.org/0000-0002-2540-2917
Chengqian LiDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266555, China.ORCID https://orcid.org/0000-0001-7821-8462
Nailong YangDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266555, China.ORCID https://orcid.org/0000-0002-4626-8219
Qingdao University · CNDezhou University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ghrelin is a gastric endocrine peptide that has been found to be involved in the process of energy homeostasis and bone physiology in recent years. To explore the effects of ghrelin on endoplasmic reticulum stress (ERS) in MC3T3E1 cells and its possible mechanism, an ERS model was induced by tunicamycin (TM) in the osteoblast line MC3T3E1. TM at 1.5

Indexed as

AMP-Activated Protein KinasesAnimalsEndoplasmic Reticulum StressGhrelinPhosphorylationAMP-Activated Protein KinasesGhrelin

Identifiers

PMID34671436
PMCPMC8523291
OpenAlexW3206134451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.