Evidence map›Paper›PMID 34671420›Full record

ArticleComputational and mathematical methods in medicine2021

Bioinformatics Analysis Reveals

Hui Ma, Zhen Liu, Honglin Li, Xuewang Guo, Sujie Guo, Pengpeng Qu, Yuquan Wang

Abstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hui MaDepartment of Gynecology, The Secondary Hospital of Tianjin Medical University, No. 23 Pingjiang Road, Hexi District, Tianjin 300211, China.ORCID https://orcid.org/0000-0002-9000-3146
Zhen LiuDepartment of Gynecology, Chifeng Municipal Hospital, Chifeng Clinical Medical School of Inner Mongolia Medical University, Chifeng 024099, China.
Honglin LiDepartment of Gynecology, The Secondary Hospital of Tianjin Medical University, No. 23 Pingjiang Road, Hexi District, Tianjin 300211, China.
Xuewang GuoDepartment of Gynecology, The Secondary Hospital of Tianjin Medical University, No. 23 Pingjiang Road, Hexi District, Tianjin 300211, China.
Sujie GuoDepartment of Gynecology, The Secondary Hospital of Tianjin Medical University, No. 23 Pingjiang Road, Hexi District, Tianjin 300211, China.
Pengpeng QuDepartment of Gynecology Oncology, Tianjin Central Hospital of Gynecology & Obstetrics, 156 Sanmalu, Nankai, Tianjin 300100, China.ORCID https://orcid.org/0000-0002-4059-7257
Yuquan WangDepartment of Gynecology, The Secondary Hospital of Tianjin Medical University, No. 23 Pingjiang Road, Hexi District, Tianjin 300211, China.ORCID https://orcid.org/0000-0002-2588-5795

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The minichromosome maintenance complex 3 (MCM3) is essential for the regulation of DNA replication and cell cycle progression. However, the expression and prognostic values of MCM3 in cervical cancer (CC) have not been well-studied. Herein, we investigated the expression patterns and survival data of MCM3 in cervical cancer patients from the ONCOMINE, GEPIA, Human Protein Atlas, UALCAN, Kaplan-Meier Plotter, and LinkedOmics databases. The expression level of MCM3 is negatively correlated with advanced tumor stage and metastatic status. Specifically, MCM3 is significantly differentially expressed between patients in stage 1 and stage 3 cervical cancer with

Indexed as

Biomarkers, TumorComputational BiologyDatabases, GeneticDisease ProgressionDNA PrimaseFemaleGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateMinichromosome Maintenance Complex Component 3Minichromosome Maintenance Complex Component 6Neoplasm StagingPrognosisRNA, MessengerUp-RegulationUterine Cervical NeoplasmsBiomarkers, TumorDNA PrimaseMCM3 protein, humanMCM6 protein, humanMinichromosome Maintenance Complex Component 3Minichromosome Maintenance Complex Component 6PRIM2 protein, humanRNA, Messenger

Identifiers

PMID34671420
PMCPMC8523256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.