PRG-1 relieves pain and depressive-like behaviors in rats of bone cancer pain by regulation of dendritic spine in hippocampus.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

1. Regional homogeneity alterations reflect pain and emotional dysregulation in adenomyosis.Annals of medicine · 2026
   Article
2. PRG-1 Relieves Neonatal Stimuli-Induced Hyperalgesia and Anxiety via Stage-Specific Synapse Remodeling.CNS neuroscience & therapeutics · 2025
   Article
3. GluR2 overexpression in ACC glutamatergic neurons alleviates cancer-induced bone pain in rats.Molecular medicine (Cambridge, Mass.) · 2025
   Article
4. MiR-18a-LncRNA NONRATG-022419 pairs targeted PRG-1 regulates diabetic induced cognitive impairment by regulating NGF\BDNF-Trkb signaling pathway.Proteome science · 2025
   Article
5. Mechanism of the analgesic effect of electroacupuncture on bone cancer pain through the neuro-immune system: progress based on animal experiments.Frontiers in neurology · 2025
   Review
6. A Study on the Association Between Risk Factors and Psychosocial Factors of Non-Cardiac Chest Pain (NCCP) in Adults Aged 40 and Above Based on 2013-2018 US NHANES Data.Journal of pain research · 2025
   Article
7. Study on the Mechanisms of Glrα3 in Pain Sensitization of Endometriosis.International journal of molecular sciences · 2024
   Article
8. DExH-box helicase 9 modulates hippocampal synapses and regulates neuropathic pain.iScience · 2024
   Article
9. PLPPR4 haploinsufficiency causes neurodevelopmental disorders by disrupting synaptic plasticity via mTOR signalling.Journal of cellular and molecular medicine · 2023
   Article
10. Emerging roles of the P2X7 receptor in cancer pain.Purinergic signalling · 2023
    Review
11. Assessing Orofacial Pain Behaviors in Animal Models: A Review.Brain sciences · 2023
    Review
12. IGF/IGF-1R signal pathway in pain: a promising therapeutic target.International journal of biological sciences · 2023
    Review
13. Pain in Huntington's disease and its potential mechanisms.Frontiers in aging neuroscience · 2023
    Review
14. Musical therapy attenuates neuroma pain by modifying leptin expression.BMC complementary medicine and therapies · 2022
    Article
15. PRG-1 prevents neonatal stimuli-induced persistent hyperalgesia and memory dysfunction via NSF/Glu/GluR2 signaling.iScience · 2022
    Article
16. A Possible Causal Involvement of Neuroinflammatory, Purinergic P2X7 Receptors in Psychiatric Disorders.Current neuropharmacology · 2022
    Article
17. Neuroinflammation in the medial prefrontal cortex exerts a crucial role in bone cancer pain.Frontiers in molecular neuroscience · 2022
    Article
18. Nanoparticulate MgHMolecular pain
    Article
19. Amino acid transporter SLC38A3 mediates bone cancer pain in rats via the PI3K/AKT/TRPV1 signaling pathway.Molecular pain
    Article

Corrections and comments

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Authors and funding

6 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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