Evidence map›Paper›PMID 34671210›Full record

ArticleInternational journal of biological sciences2021

Li-Jie Chen, Xiu-Xian Lin, Jing Guo, Ying Xu, Song-Xia Zhang, Dan Chen, Qing Zhao, Jian Xiao, Guang-Hui Lian, Shi-Fang Peng and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. CRISPR/Cas9-Mediated Disruption ofInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Li-Jie ChenDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Xiu-Xian LinDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Jing GuoDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Ying XuDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Song-Xia ZhangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Dan ChenDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Qing ZhaoDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Jian XiaoDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Guang-Hui LianDepartment of gastroenterology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Shi-Fang PengDepartment of Hepatology and Infectious Diseases, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Dong GuoDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201. USA.
Hong YangDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201. USA.
Yan ShuDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201. USA.
Hong-Hao ZhouDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Wei ZhangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Yao ChenDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
Central South University · CNNational Clinical Research Center for Digestive Diseases · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Predisposition to DiseaseAdultAnimalsbeta CateninCatsCytochrome P-450 CYP2E1FemaleGenotypeHumansLow Density Lipoprotein Receptor-Related Protein-6MaleNon-alcoholic Fatty Liver DiseaseSignal TransductionSilybinWnt Signaling Pathwaybeta CateninCTNNB1 protein, humanCytochrome P-450 CYP2E1Low Density Lipoprotein Receptor-Related Protein-6LRP6 protein, humanSilybincytochrome P450 2e1genotypelow-density lipoprotein receptor-related protein 6nonalcoholic fatty liver diseasereactive oxygen species

Identifiers

PMID34671210
PMCPMC8495406
OpenAlexW3209102319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.