ArticleNature communications2021
Spared perilesional V1 activity underlies training-induced recovery of luminance detection sensitivity in cortically-blind patients.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Training in Cortically Blinded Fields Appears to Confer Patient-Specific Benefit Against Retinal Thinning.Investigative ophthalmology & visual science · 2024Pooled it
- Boosting hemianopia recovery: the power of interareal cross-frequency brain stimulation.Brain : a journal of neurology · 2025Trial
- Pathway-dependent brain stimulation responses indicate motion processing integrity after stroke.Brain : a journal of neurology · 2025Trial
- From error to evidence: blindsight in the making†.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Generalisation of training-induced recovery in occipital stroke: neurochemical and fMRI correlates.bioRxiv : the preprint server for biology · 2026Article
- Uncertainty in population receptive field estimates revealed by variational qPRF.Journal of neuroscience methods · 2026Article
- Dynamic neural compensation for distorted orientation perception in chronic astigmatism.iScience · 2025Article
- What V1 Damage Can Teach Us About Visual Perception and Learning.Annual review of vision science · 2025Review
- Quantification of retinotopic maps with a Gaussian process modeling.Journal of vision · 2025Article
- Evolution of Visual Field Defects After Occipital Stroke: A Quantitative Analysis.Translational vision science & technology · 2025Article
- Exogenous Spatial Attention Helps Overcome Spatial Specificity of Visual Learning in the Blind Field After V1 Damage.Journal of cognitive enhancement : towards the integration of theory and practice · 2025Article
- Voxel-Based Lesion-Symptom Mapping Localizes Residual Visual Function in Hemianopia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- qPRF: A system to accelerate population receptive field modeling.NeuroImage · 2025Article
- Improving the reliability and accuracy of population receptive field measures using a logarithmically warped stimulus.Journal of vision · 2025Article
- A telerehabilitation program to improve visual perception in children and adolescents with hemianopia consecutive to a brain tumor: a single-arm feasibility and proof-of-concept trial.EClinicalMedicine · 2024Article
- The Role of Population Receptive Field Sizes in Higher-Order Visual Dysfunction.Current neurology and neuroscience reports · 2024Review
- MAIA and Humphrey Perimetry Differ in Their Estimation of Homonymous Visual Field Defects.Translational vision science & technology · 2024Article
- qPRF: A system to accelerate population receptive field decoding.bioRxiv : the preprint server for biology · 2024Article
- Improving the Reliability and Accuracy of Population Receptive Field Measures Using a Logarithmically Warped Stimulus.bioRxiv : the preprint server for biology · 2024Article
- Rehabilitating homonymous visual field deficits: white matter markers of recovery-stage 2 registered report.Brain communications · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Damage to the primary visual cortex (V1) causes homonymous visual-field loss long considered intractable. Multiple studies now show that perceptual training can restore visual functions in chronic cortically-induced blindness (CB). A popular hypothesis is that training can harness residual visual functions by recruiting intact extrageniculostriate pathways. Training may also induce plastic changes within spared regions of the damaged V1. Here, we link changes in luminance detection sensitivity with retinotopic fMRI activity before and after visual discrimination training in eleven patients with chronic, stroke-induced CB. We show that spared V1 activity representing perimetrically-blind locations prior to training predicts the amount of training-induced recovery of luminance detection sensitivity. Additionally, training results in an enlargement of population receptive fields in perilesional V1, which increases blind-field coverage and may support further recovery with subsequent training. These findings uncover fundamental changes in perilesional V1 cortex underlying training-induced restoration of conscious luminance detection sensitivity in CB.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.