Evidence map›Paper›PMID 34670904›Full record

ArticleInternal medicine (Tokyo, Japan)2022

CV2/CRMP5-antibody-related Paraneoplastic Neurologic Syndrome Associated with Gastrointestinal Stromal Tumor.

Hirofumi Fukushima, Tomoyoshi Shibuya, Takahito Awatsu, Taro Kurosawa, Keiichi Haga, Takashi Murakami, Nobuko Serizawa, Akio Mori, Mariko Hojo, Takashi Yao and 2 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Hirofumi FukushimaDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Tomoyoshi ShibuyaDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Takahito AwatsuDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Taro KurosawaDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Keiichi HagaDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Takashi MurakamiDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Nobuko SerizawaDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Akio MoriDepartment of Neurology, Juntendo University School of Medicine, Japan.
Mariko HojoDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Takashi YaoDepartment of Human Pathology, Juntendo University School of Medicine, Japan.
Nobutaka HattoriDepartment of Neurology, Juntendo University School of Medicine, Japan.
Akihito NagaharaDepartment of Gastroenterology, Juntendo University School of Medicine, Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraneoplastic neurological syndrome (PNS) is a heterogeneous group of neurological disorders caused by immune-mediated inflammatory mechanisms. We herein report a 77-year-old man with CV2/CRMP5-antibody-related PNS associated with a gastrointestinal stromal tumor (GIST). He was admitted for forgetfulness and delusional behavior. His neurological symptoms were subacute, and a whole-body examination revealed a gastric GIST. Serology showed CV2/collapsin response mediator protein (CRMP)-5 antibodies. Partial gastrectomy was performed for the GIST, and the neurological symptoms and serum CV2/CRMP5 antibodies disappeared. No relapse has occurred since the surgery. PNS should be considered in patients with subacute neurological disorders.

Indexed as

Gastrointestinal Stromal TumorsNervous System DiseasesParaneoplastic SyndromesParaneoplastic Syndromes, Nervous SystemAgedAutoantibodiesHumansMaleNeoplasm Recurrence, LocalAutoantibodiesCV2/CRMP5 antibodiesdeveloped limbic encephalitisgastrointestinal stromal tumorparaneoplastic neurologic syndrome

Identifiers

PMID34670904
PMCPMC9177369
OpenAlexW3207947938

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.