Evidence map›Paper›PMID 34670889›Full record

ReviewInternal medicine (Tokyo, Japan)2022

Clinical Characteristics and Predictors Related to the Progression of Multinodular Goiter Causing Tracheal Compression and Deviation: A Report of Two Cases and Review of the Literature.

Toshihiro Takamori, Shoichiro Izawa, Takahiro Fukuhara, Akemi Sato, Hitomi Ichikawa, Toru Motokura, Kazuhiro Yamamoto, Tetsuya Fukuda

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Clinical characteristics of multinodular goiter causing tracheal compression.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Redo Thyroidectomy: Updated Insights.Journal of clinical medicine · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Toshihiro TakamoriDivision of Clinical Laboratory, Tottori University Hospital, Japan.
Shoichiro IzawaDivision of Endocrinology and Metabolism, Tottori University Faculty of Medicine, Japan.
Takahiro FukuharaDepartment of Otolaryngology, Head and Neck Surgery, Tottori University Faculty of Medicine, Japan.
Akemi SatoDivision of Clinical Laboratory, Tottori University Hospital, Japan.
Hitomi IchikawaDivision of Clinical Laboratory, Tottori University Hospital, Japan.
Toru MotokuraDivision of Clinical Laboratory Medicine, Tottori University Faculty of Medicine, Japan.
Kazuhiro YamamotoDivision of Endocrinology and Metabolism, Tottori University Faculty of Medicine, Japan.
Tetsuya FukudaDivision of Clinical Laboratory, Tottori University Hospital, Japan.
Tottori University · JPTottori University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the clinical course of two patients who developed tracheal compression and deviation by multinodular goiter (MNG). Case 1: A 66-year-old woman presented with thyroid swelling. Five years after the initial admission, she was diagnosed with hyperthyroidism by Graves' disease and increased bilateral thyroid lobes compressing the trachea. Thyroglobulin was elevated from 210 to 472 ng/mL. Case 2: A 52-year-old woman presented with thyroid swelling. Five years after the initial admission, the increased right lobe deviated the trachea and compressed the right recurrent laryngeal nerve. Thyroglobulin was elevated from 122 to 392 ng/mL. Two cases and literature review indicated that MNG with >50 mm, solid components, and extension to the mediastinum or paralarynx were risk factors of tracheal compression and deviation. Monitoring thyroglobulin elevation can help predict the clinical course.

Indexed as

GoiterGoiter, NodularGraves DiseaseHyperthyroidismAgedFemaleHumansMiddle AgedThyroglobulinThyroglobulinhyperthyroidismmultinodular goiterthyroglobulintracheal compressiontracheal deviation

Identifiers

PMID34670889
PMCPMC9152857
OpenAlexW3206046629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.