Evidence map›Paper›PMID 34670887›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Effective Treatment of Adult Parasomnias with Keishikaryukotsuboreito in Four Cases.

Mayumi Tamada, Shinji Ueno, Kako Watanabe, Shin-Ichi Muramatsu

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mayumi TamadaDivision of Oriental Medicine, Center for Community Medicine, Jichi Medical University, Japan.
Shinji UenoDivision of Oriental Medicine, Center for Community Medicine, Jichi Medical University, Japan.
Kako WatanabeAzabu Muse Clinic, Japan.
Shin-Ichi MuramatsuDivision of Oriental Medicine, Center for Community Medicine, Jichi Medical University, Japan.
Jichi Medical University · JPAzabu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parasomnias are undesirable behaviors or experiences during sleep that manifest clinically as abnormal behavior, emotions, and nightmares. We herein report four elderly parasomnia patients who were successfully treated for abnormal nocturnal behaviors, including rapid eye movement (REM) sleep behavior disorders, with Keishikaryukotsuboreito (KRB), a Japanese traditional herbal medicine. KRB resolved nocturnal violent behaviors and sleep walking without any adverse effects. In one patient, occipital dominant spike-wave complexes induced by 3-Hz photic stimulation were reduced after KRB treatment, suggesting that KRB has inhibitory effects on brain irritability. KRB may represent a safe therapeutic option for treating parasomnias in the elderly.

Indexed as

ParasomniasSleep Wake DisordersAdultAgedHumansSleepKeisikaryukotsuboreitoparasomniaREM sleep behavior disorder

Identifiers

PMID34670887
PMCPMC9152866
OpenAlexW3206983469

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.