ReviewGut and liver2022
Type 2 Autoimmune Pancreatitis: Consensus and Controversies.
Review in Gut and liver, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Immune checkpoint inhibitors-induced pancreatitis: a systematic review and real-world pharmacovigilance analysis.Frontiers in pharmacology · 2025Pooled it
- Unraveling the relationship between autoimmune pancreatitis type 2 and inflammatory bowel disease: Results from two centers and systematic review of the literature.United European gastroenterology journal · 2022Pooled it
- Multifocal autoimmune pancreatitis complicated by pancreatic insufficiency and segmental portal hypertension: A case report and review of the literature.Radiology case reports · 2026Article
- Renal Mucosa-Associated Lymphoid Tissue Lymphoma Mimicking Autoimmune Pancreatitis: A Diagnostic Challenge.ACG case reports journal · 2026Article
- A Tangled Tale: Type 2 Autoimmune Pancreatitis With a Sclerosing Twist.ACG case reports journal · 2026Article
- Autoimmune Pancreatitis Re-Classification with Novel Type AIP-4.International journal of molecular sciences · 2026Review
- Case Report: Recurrent abdominal pain with elevated pancreatic enzymes in type 2 diabetes mellitus: a case of IgG4-related autoimmune pancreatitis misdiagnosed as acute pancreatitis.Frontiers in endocrinology · 2026Article
- Systematic Approach to Treatment of Chronic Pancreatitis.Gastroenterology & hepatology · 2026Article
- CT findings in surgically treated focal pancreatic disease - a retrospective study.Annals of medicine and surgery (2012) · 2025Article
- Advances in MRI in the Evaluation of Chronic Pancreatitis and the Less Common Forms of Pancreatitis.Advances in clinical radiology · 2025Article
- Endoscopic Diagnostics for IgG4-Related Pancreatobiliary Diseases: Current Modalities and Clinical Perspectives.Diagnostics (Basel, Switzerland) · 2025Review
- Update on Autoimmune Pancreatitis and IgG4-Related Disease.United European gastroenterology journal · 2025Review
- Erdheim-Chester Disease with Pancreatic Enlargement Observed Using Contrast-enhanced Endoscopic Ultrasonography.Internal medicine (Tokyo, Japan) · 2025Article
- Mass-forming type 2 autoimmune pancreatitis with upstream dilatation of the main pancreatic duct dilatation: a case report.Journal of medical case reports · 2024Article
- Autoimmune Pancreatitis Type 2, Biliary Cysts andChildren (Basel, Switzerland) · 2024Article
- Clinical features and long-term outcomes of patients with type 2 autoimmune pancreatitis.United European gastroenterology journal · 2024Observational
- Autoimmune pancreatitis: Cornerstones and future perspectives.World journal of gastroenterology · 2024Review
- A Rare Case of Autoimmune Pancreatitis in a 9-Year-Old Male Patient: A Comprehensive Diagnosis and Successful Treatment.Case reports in gastrointestinal medicine · 2024Article
- Is Surgery in Autoimmune Pancreatitis Always a Failure?Medicina (Kaunas, Lithuania) · 2023Review
- Type 2 autoimmune pancreatitis associated with ulcerative colitis.Frontiers in immunology · 2023Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autoimmune pancreatitis (AIP) has attracted much attention in the last two decades, and due to the diagnostic value of immunoglobulin G4 (IgG4), the number of cases diagnosed in clinical practice has markedly increased. However, in contrast to prototypic IgG4-related type 1 AIP, a minor subtype of AIP, referred to as type 2 AIP, is less widely known and has thus not yet been characterized in detail. Type 2 AIP is unrelated to IgG4 and is a completely distinct entity from type 1 AIP. One confusing factor is that the two types of AIP share patterns of clinical presentation (e.g., acute pancreatitis and painless jaundice) and imaging abnormalities (e.g., diffuse or segmental enlargement). Since there are currently no established serum markers, the diagnosis of type 2 AIP is highly challenging and requires the tissue confirmation of neutrophilic injury to the pancreatic ducts, a finding designated as a granulocytic epithelial lesion. Approximately one-third of cases are associated with inflammatory bowel disease, particularly ulcerative colitis; however, the pathological relationship between these two conditions has not yet been clarified. Unanswered questions relate to its pathophysiology, the potential development of a similar granulocytic injury in other organs, and the characteristics of pediatric cases. This review summarizes consensus and controversies surrounding type 2 AIP, with the aim of increasing awareness and highlighting the unmet needs of this underrecognized condition.
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