Evidence map›Paper›PMID 34670863›Full record

ArticleMolecular cancer research : MCR2022

Ecdysoneless Protein Regulates Viral and Cellular mRNA Splicing to Promote Cervical Oncogenesis.

Sameer Mirza, Achyuth Kalluchi, Mohsin Raza, Irfana Saleem, Bhopal Mohapatra, Dhananjaya Pal, Michel M Ouellette, Fang Qiu, Lulu Yu, Alexei Lobanov and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Sameer Mirza *Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska.
Achyuth Kalluchi *Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska.
Mohsin RazaDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska.
Irfana SaleemDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska.
Bhopal MohapatraDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska.
Dhananjaya PalDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska.
Michel M OuelletteDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska.
Fang QiuFred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska.
Lulu YuTumor Virus RNA Biology Section, HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland.
Alexei LobanovCCR Collaborative Bioinformatics Resource (CCBR), National Cancer Institute, Bethesda, Maryland.
Zhi-Ming ZhengTumor Virus RNA Biology Section, HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland.ORCID 0000-0001-5547-7912
Ying ZhangNorthshore University Health System, Chicago, Illinois.
Mansour A AlsaleemDepartment of Pathology, School of Medicine, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0002-7689-2493
Emad A RakhaDepartment of Pathology, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Hamid BandDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska. vband@unmc.edu hband@unmc.edu jordan.rowley@unmc.edu.ORCID 0000-0002-4996-9002
M Jordan RowleyDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska. vband@unmc.edu hband@unmc.edu jordan.rowley@unmc.edu.ORCID 0000-0002-5135-9596
Vimla BandDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska. vband@unmc.edu hband@unmc.edu jordan.rowley@unmc.edu.
University of Nebraska Medical Center · USNational Cancer Institute · USNebraska Medical Center · USUniversity of Nottingham · GBNorthShore University HealthSystem · US

Funding

UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Joann B. Sweasy · 1985 to 2026
$55.0M
Gene Expression and Post-Transcriptional Regulation of DNA Tumor VirusesZIASC010357 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI ZHENG, ZHI-MING · 2009 to 2025
$24.3M
Principals of Chromatin OrganizationR00GM127671 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI ROWLEY, MICHAEL JORDAN · 2019 to 2021
$747k
Ecdysoneless, A Novel Regulator of Androgen ReceptorR21CA241055 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAND, VIMLA · 2019 to 2020
$379k
NCI NIH HHS P30 CA036727NCI NIH HHS R21 CA241055NIGMS NIH HHS R00 GM127671
6 · The paper itself

Abstract

High-risk human papillomaviruses (HPV), exemplified by HPV16/18, are causally linked to human cancers of the anogenital tract, skin, and upper aerodigestive tract. Previously, we identified Ecdysoneless (ECD) protein, the human homolog of the

Indexed as

Carrier ProteinsFemaleHumansOncogenesRNA, MessengerRNA SplicingTransfectionUterine Cervical NeoplasmsCarrier ProteinsECD protein, humanRNA, Messenger

Identifiers

PMID34670863
PMCPMC9138181
OpenAlexW3206432561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.