Evidence map›Paper›PMID 34670555›Full record

ArticleEnvironmental health : a global access science source2021

Respiratory function declines in children with asthma associated with chemical species of fine particulate matter (PM

Yoonhee Kim, Eun Ha Park, Chris Fook Sheng Ng, Yeonseung Chung, Kunio Hashimoto, Kasumi Tashiro, Hideki Hasunuma, Masataka Doi, Kei Tamura, Hiroyuki Moriuchi and 5 more

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  3. Long-term PMERJ open research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yoonhee KimDepartment of Global Environmental Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Eun Ha ParkInstitute of Health and Environment, Seoul National University, Seoul, South Korea.
Chris Fook Sheng NgSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Yeonseung ChungDepartment of Mathematical Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Kunio HashimotoDepartment of Paediatrics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Kasumi TashiroDepartment of Paediatrics, Isahaya General Hospital, Nagasaki, Japan.
Hideki HasunumaDepartment of Public Health, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
Masataka DoiKenhoku Healthcare Office, Nagasaki Prefectural Government, Nagasaki, Japan.
Kei TamuraPharmaceutical Administration Office, Nagasaki Prefectural Government, Nagasaki, Japan.
Hiroyuki MoriuchiDepartment of Paediatrics, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Yuji NishiwakiDepartment of Environmental and Occupational Health, School of Medicine, Toho University, Tokyo, Japan.
Hwajin KimGraduate School of Public Health, Seoul National University, Seoul, South Korea.
Seung-Muk YiGraduate School of Public Health, Seoul National University, Seoul, South Korea.
Ho KimGraduate School of Public Health, Seoul National University, Seoul, South Korea.
Masahiro HashizumeSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan. hashizume@m.u-tokyo.ac.jp.ORCID 0000-0003-4720-1750

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe differential effects of PM

methodsWe conducted a multiyear panel study of 73 asthmatic children (boys, 60.3%; mean age, 8.2 years) spanning spring 2014-2016 in two cities. We collected self-measured peak expiratory flow (PEF) twice a day and daily time-series data for PM

resultsWe found that morning PEFs were adversely associated with higher levels of sulfate (- 1.61 L/min; 95% CI: - 3.07, - 0.15) in Nagasaki city and organic carbon (OC) (- 1.02 L/min; 95% CI: - 1.94, - 0.09) in Isahaya city, per interquartile range (IQR) increase at lag1. In addition, we observed consistent findings for worsening asthma, with higher odds of severe PEF decline in the morning for sulfate (odds ratio (OR) = 2.31; 95% CI: 1.12, 4.77) and ammonium (OR = 1.73; 95% CI: 1.06, 2.84) in Nagasaki city and OC (OR = 1.51; 95% CI: 1.06, 2.15) in Isahaya city, per IQR increase at lag1. The significant chemical species were higher on days that could be largely attributed to the path of Northeast China origin (for sulfate and ammonium) or both the same path and local sources (for OC) than by other clusters.

conclusionsThis study provides evidence of the differential effects of PM

Indexed as

Air PollutantsAir PollutionAsthmaChildChinaEnvironmental ExposureHumansJapanMaleParticulate MatterAir PollutantsParticulate MatterAsthmaChemical compositionChildrenLung functionParticulate matter

Identifiers

PMID34670555
PMCPMC8529805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.