SynthesisBMC ecology and evolution2021
Direct evidence for increased disease resistance in polyandrous broods exists only in eusocial Hymenoptera.
Synthesis in BMC ecology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
- Positive selection in cytochrome P450 genes is associated with gonad phenotype and mating strategy in social bees.Scientific reports · 2023Article
- Genetic diversity and disease: The past, present, and future of an old idea.Evolution; international journal of organic evolution · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe 'genetic diversity' hypothesis posits that polyandry evolved as a mechanism to increase genetic diversity within broods. One extension of this hypothesis is the 'genetic diversity for disease resistance' hypothesis (GDDRH). Originally designed for eusocial Hymenoptera, GDDRH states that polyandry will evolve as an effect of lower parasite prevalence in genetically variable broods. However, this hypothesis has been broadly applied to several other taxa. It is unclear how much empirical evidence supports GDDRH specifically, especially outside eusocial Hymenoptera.
resultsThis question was addressed by conducting a literature review and posteriorly conducting meta-analyses on the data available using Hedges's g. The literature review found 10 direct and 32 indirect studies with both having a strong publication bias towards Hymenoptera. Two meta-analyses were conducted and both found increased polyandry (direct tests; n = 8, g = 0.2283, p = < 0.0001) and genetic diversity generated by other mechanisms (indirect tests; n = 10, g = 0.21, p = < 0.0001) reduced parasite load. A subsequent moderator analysis revealed that there were no differences among Orders, indicating there may be applicability outside of Hymenoptera. However, due to publication bias and low sample size we must exercise caution with these results.
conclusionDespite the fact that the GDDRH was developed for Hymenoptera, it is frequently applied to other taxa. This study highlights the low amount of direct evidence supporting GDDRH, particularly outside of eusocial Hymenoptera. It calls for future research to address species that have high dispersal rates and contain mixes of solitary and communal nesting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.