Evidence map›Paper›PMID 34670413›Full record

ArticleGlobal spine journal2023

Surgery for Metastatic Spinal Disease in Octogenarians and Above: Analysis of 78 Patients.

Ibrahim Hussain, Benjamin R Hartley, Lily McLaughlin, Anne S Reiner, Ilya Laufer, Mark H Bilsky, Ori Barzilai

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Do we need a neurosurgical frailty index?Surgical neurology international · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ibrahim HussainDepartment of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-6343-2228
Benjamin R HartleyDepartment of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lily McLaughlinDepartment of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Anne S ReinerDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-1258-6112
Ilya LauferDepartment of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Mark H BilskyDepartment of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ori BarzilaiDepartment of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

STUDY

designRetrospective Cohort Study.

objectiveOctogenarians living with spinal metastases are a challenging population to treat. Our objective was to identify the rate, types, management, and predictors of complications and survival in octogenarians following surgery for spinal metastases.

methodsA retrospective review of a prospectively collected cohort of patients aged 80 years or older who underwent surgery for metastatic spinal tumor treatment between 2008 and 2019 were included. Demographic, intraoperative, complications, and postoperative follow-up data was collected. Cox proportional hazards regression and logistic regression were used to associate variables with overall survival and postoperative complications, respectively.

results78 patients (mean 83.6 years) met inclusion criteria. Average operative time and blood loss were 157 minutes and 615 mL, respectively. The median length of stay was 7 days. The overall complication rate was 31% (N = 24), with 21% considered major and 7% considered life-threatening or fatal. Blood loss was significantly associated with postoperative complications (OR = 1.002;

conclusionsIn octogenarians undergoing surgery with instrumentation for spinal metastases, the median overall survival is 11.6 months. There is an increased complication rate, but only 7% are life-threatening or fatal. Patients are at increased risk for complications and mortality particularly when performing decompression with stabilization, with increasing intraoperative blood loss, and with cervical/cervicothoracic tumors.

Indexed as

elderlyoctogenarianpercutaneous stabilizationseparation surgeryspinal metastasisspine tumor

Identifiers

PMID34670413
PMCPMC10448094
OpenAlexW3205801215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.