ArticleEpigenomics2021
Per- and polyfluoroalkyl substances, epigenetic age and DNA methylation: a cross-sectional study of firefighters.
Open access · greenAbstract read
In one paragraph
Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Epigenetic Changes Induced by Carcinogenic Agents or Occupational Exposure with Sufficient Evidence for Bladder Cancer.Cancer prevention research (Philadelphia, Pa.) · 2025Pooled it
- Known and Novel Per/Polyfluoroalkyl Substances (PFASs) in Serum of Tucson (AZ) Firefighters.Environmental science & technology · 2026Article
- Serum PFAS in Aircraft Rescue and Firefighting (ARFF) Firefighters From Six U.S. Airport Fire Departments.American journal of industrial medicine · 2026Article
- Predictors of Serum Per- and Polyfluoroalkyl Substances (PFAS) Levels Among US Career Firefighters.Journal of occupational and environmental medicine · 2026Article
- PFAS Toxicity: What's True, What's Not, and What Really Matters.Environmental science & technology · 2026Review
- Article
- Associations between per- and polyfluoroalkyl substances (PFAS), DNA methylation and gene expression from background exposed Norwegian women (2003-2006).Scientific reports · 2026Article
- Role of one-carbon metabolism variants in the associations between perfluoroalkyl substances exposure and birth size in the Taiwan Birth Panel Study.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Models and challenges for studying forever chemicals and their impact on human health.Disease models & mechanisms · 2025Review
- Socioeconomic Disparities and Risk of Papillary Thyroid Cancer Associated with Environmental Exposure to Per- and Polyfluoroalkyl Substances (PFAS) in Florida.International journal of environmental research and public health · 2025Article
- Sex-specific associations between per- and polyfluoroalkyl substance exposure and epigenetic age: Findings from the National Health and Nutrition Examination survey 1999-2000.Environmental research · 2025Article
- Per- and polyfluoroalkyl substances (PFAS) and microRNA: An epigenome-wide association study in firefighters.Environmental research · 2025Article
- Perinatal Exposure to Lead or Diethylhexyl Phthalate in Mice: Sex-Specific Effects on Cardiac DNA Methylation and Gene Expression across Time.Environmental health perspectives · 2025Article
- The Fire Fighter Cancer Cohort Study: Protocol for a Longitudinal Occupational Cohort Study.JMIR research protocols · 2025Article
- Interventions to Reduce Serum Per- and Poly-Fluoroalkyl Substances Levels, Improve Cardiovascular Risk Profiles, and Improve Epigenetic Age Acceleration in US Firefighters: Protocol for Randomized Controlled Trial.JMIR research protocols · 2025Article
- Sex-specific effects of in utero exposure to per- and polyfluoroalkyl substances on placental development.Environmental research · 2025Article
- Environmental Health Is Overlooked in Longevity Research.Antioxidants (Basel, Switzerland) · 2025Review
- Serum levels of per- and polyfluoroalkylated substances and methylation of DNA from peripheral blood.Frontiers in public health · 2025Article
- Emerging PFAS contaminants PFNA and PFSA amplify epigenetic aging: sex- and age-stratified risks in an aging population.Frontiers in aging · 2025Article
- Maternal Nutrition, Toxicants, and Epigenetic Programming of Obesity Across Generations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 10 institutions in 1 country.
Jaclyn M GoodrichDepartment of Environmental Health Sciences, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA.ORCID 0000-0002-8289-9253
Miriam M CalkinsNational Institute for Occupational Safety & Health, Centers for Disease Control & Prevention, Cincinnati, OH 45226, USA.
Alberto J Caban-MartinezDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-5960-1308
Todd StueckleNational Institute for Occupational Safety & Health, Centers for Disease Control & Prevention, Morgantown, WV 26505, USA.
Casey GrantFire Protection Research Foundation, Quincy, MA 02169, USA.
Antonia M CalafatNational Center for Environmental Health, Centers for Disease Control & Prevention, Atlanta, GA 30341, USA.
Amy NematollahiDepartment of Community, Environment & Policy, University of Arizona Mel & Enid Zuckerman College of Public Health, Tucson, AZ 85724, USA.
Alesia M JungDepartment of Epidemiology & Biostatistics, University of Arizona Mel & Enid Zuckerman College of Public Health, Tucson, AZ 85724, USA.
Judith M GraberDepartment of Biostatistics & Epidemiology, Rutgers the State University of New Jersey, Piscataway, NJ 08854, USA.
Timothy JenkinsDepartment of Cell Biology & Physiology, Brigham Young University, Provo, UT 84602, USA.
Angela L SlittDepartment of Biomedical Sciences, University of Rhode Island College of Pharmacy, Kingston, RI 02881, USA.
Alisa DewaldDepartment of Environmental Health Sciences, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA.
Julianne Cook BotelhoNational Center for Environmental Health, Centers for Disease Control & Prevention, Atlanta, GA 30341, USA.
Shawn BeitelDepartment of Community, Environment & Policy, University of Arizona Mel & Enid Zuckerman College of Public Health, Tucson, AZ 85724, USA.
Sally LittauDepartment of Community, Environment & Policy, University of Arizona Mel & Enid Zuckerman College of Public Health, Tucson, AZ 85724, USA.
John GulottaTucson Fire Department, Tucson, AZ 85701, USA.
Darin WallentineTucson Fire Department, Tucson, AZ 85701, USA.
Jeff HughesOrange County Fire Authority, Irvine, CA 92602, USA.
Charles PoppBoston Fire Department, Boston, MA 02118, USA.
Jefferey L BurgessDepartment of Community, Environment & Policy, University of Arizona Mel & Enid Zuckerman College of Public Health, Tucson, AZ 85724, USA.
University of Arizona · USNew York City Fire Department · USNational Center for Environmental Health · USNational Institute for Occupational Safety and Health · USUniversity of Michigan · USBrigham Young University · USNational Fire Protection Association · USRutgers, The State University of New Jersey · USUniversity of Miami · USUniversity of Rhode Island · US
Funding
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI George S Watts · 1994 to 2026
$36.7MStrategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3MTraining in Environmental Toxicology of Human DiseaseT32ES007091 · NIEHS · UNIVERSITY OF ARIZONA · PI Nathan J Cherrington · 1985 to 2026
$10.7MFEMA DHS FEMA999999NIEHS NIH HHS P30 ES006694NIEHS NIH HHS P30 ES017885NIEHS NIH HHS T32 ES007091
Abstract
PubMed holds no abstract for this paper.
Indexed as
DNA MethylationEpigenesis, GeneticFirefightersBiomarkersBlood CellsDisease SusceptibilityFemaleHazardous SubstancesHealth Impact AssessmentHumansMaleOccupational ExposurePublic Health SurveillanceRisk AssessmentBiomarkersHazardous Substancesenvironmental exposuresepigenetic ageepigenomicsfirefighteroccupational exposuresper- and polyfluoroalkyl substances
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.