Evidence map›Paper›PMID 34670359›Full record

ArticleHaematologica2022

Tumor suppressor function of

Matthew J Christopher, Casey D S Katerndahl, Hayley R LeBlanc, Tyler T Elmendorf, Vaishali Basu, Margery Gang, Andrew J Menssen, David H Spencer, Eric J Duncavage, Shamika Ketkar and 4 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Matthew J ChristopherSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO. christopherm@wustl.edu.
Casey D S KaterndahlSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Hayley R LeBlancSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Tyler T ElmendorfSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Vaishali BasuSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Margery GangSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Andrew J MenssenSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
David H SpencerSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Eric J DuncavageDepartment of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO.
Shamika KetkarSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO; Current affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX.
Lukas D WartmanSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Sai Mukund RamakrishnanSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Christopher A MillerSection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Timothy J LeySection of Stem Cell Biology, Division of Oncology, Department of Internal Medicine, Washington University in St. Louis, St. Louis, MO.
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
Specimen Acquistition and Expression ProfilingP01CA101937 · NCI · WASHINGTON UNIVERSITY · PI LINK, DANIEL C · 2003 to 2023
$58.8M
Targeting the Bone Marrow Microenvironment In Acute Lymphocytic LeukemiaP50CA171963 · NCI · WASHINGTON UNIVERSITY · PI Daniel C Link · 2013 to 2026
$31.6M
PRE-AND POSTGRADUATE TRAINING IN MOLECULAR HEMATOLOGYT32HL007088 · NHLBI · WASHINGTON UNIVERSITY · PI Grant Anthony Challen, Stephen Oh · 1985 to 2026
$14.1M
Washington University Paul Calabresi K12 Career Development Award for Clinical OncologyK12CA167540 · NCI · WASHINGTON UNIVERSITY · PI John F. Dipersio, Ramaswamy Govindan · 2012 to 2026
$11.7M
Molecular Pathogenesis of Acute Myeloid LeukemiaR35CA197561 · NCI · WASHINGTON UNIVERSITY · PI Timothy J. Ley · 2015 to 2026
$11.0M
COMPREHENSIVE INFORMATIC ANALYSES OF AML GENOMES AND EPIGENOMESR50CA211782 · NCI · WASHINGTON UNIVERSITY · PI Christopher A Miller · 2017 to 2026
$1.5M
REGULATORY MECHANISMS OF HOX GENE EXPRESSION IN ACUTE MYELOID LEUKEMIAK08CA190815 · NCI · WASHINGTON UNIVERSITY · PI SPENCER, DAVID H · 2015 to 2019
$831k
MUTANT AND WILD TYPE WT1 IN AMLK08CA222630 · NCI · WASHINGTON UNIVERSITY · PI CHRISTOPHER, MATTHEW · 2017 to 2021
$689k
NCI NIH HHS K08 CA190815NCI NIH HHS K08 CA222630NCI NIH HHS K12 CA167540NCI NIH HHS P01 CA101937NCI NIH HHS P30 CA091842NCI NIH HHS P50 CA171963NCI NIH HHS R35 CA197561NCI NIH HHS R50 CA211782NHLBI NIH HHS T32 HL007088
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukemia, Promyelocytic, AcuteWT1 ProteinsGenes, Tumor SuppressorHumansWT1 protein, humanWT1 Proteins

Identifiers

PMID34670359
PMCPMC8719088
OpenAlexW3207016057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.