Evidence map›Paper›PMID 34670078›Full record

ReviewBiochemistry2021

Ins and Outs: Recent Advancements in Membrane Protein-Mediated Prokaryotic Ferrous Iron Transport.

Janae B Brown, Mark A Lee, Aaron T Smith

Open access · greenAbstract readReview
In one paragraph

Review in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. The structure of the full catalytic cycle ofbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. BioIron: Origin, Chemical Properties, and Biological Functions.Advances in experimental medicine and biology · 2025
    Review
  8. Review
  9. TheJournal of bacteriology · 2024
    Article
  10. Structural Determinants ofbioRxiv : the preprint server for biology · 2024
    Article
  11. ThebioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Functional Characterization of the CoApplied and environmental microbiology · 2023
    Article
  17. Iron homeostasis inMicrobiology (Reading, England) · 2023
    Article
  18. Article
  19. Reconsidering theACS bio & med chem Au · 2022
    Article
  20. The structure of Vibrio cholerae FeoC reveals conservation of the helix-turn-helix motif but not the cluster-binding domain.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Janae B BrownDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, Maryland 21250, United States.
Mark A LeeDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, Maryland 21250, United States.
Aaron T SmithDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, Maryland 21250, United States.ORCID 0000-0002-9332-8683
University of Maryland, Baltimore County · US

Funding

Graduate Training at The Chemistry Biology InterfaceT32GM066706 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SELEY-RADTKE, KATHERINE L, SMITH, AARON T · 2004 to 2023
$3.3M
NIGMS NIH HHS T32 GM066706
6 · The paper itself

Abstract

Iron is an essential nutrient for virtually every living organism, especially pathogenic prokaryotes. Despite its importance, however, both the acquisition and the export of this element require dedicated pathways that are dependent on oxidation state. Due to its solubility and kinetic lability, reduced ferrous iron (Fe

Indexed as

Anti-Bacterial AgentsBacteriaBiological TransportCatalysisHomeostasisIon TransportIronKineticsMembrane ProteinsMembrane Transport ProteinsOxidation-ReductionOxidative StressProkaryotic CellsReactive Oxygen SpeciesSolubilityVirulenceAnti-Bacterial AgentsIronMembrane ProteinsMembrane Transport ProteinsReactive Oxygen Species

Identifiers

PMID34670078
PMCPMC8979593
OpenAlexW3206639490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.