ArticlePloS one2021
Lumpy skin disease outbreaks in Egypt during 2017-2018 among sheeppox vaccinated cattle: Epidemiological, pathological, and molecular findings.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Epidemiological Study and Molecular Characterization of Lumpy Skin Disease in Cattle in Egypt.Veterinary medicine international · 2026Article
- Clinical study and the diagnosis of lumpy skin disease in cattle using genomic, immunological, and pathological indicators.Frontiers in veterinary science · 2026Article
- Lumpy Skin Disease Virus (LSDV): evaluating global impact, Ethiopia's response strategies, and the promise of gamma-ray inactivated vaccines.Tropical animal health and production · 2025Review
- Development of a double-antigen sandwich ELISA for rapid and accurate detection of antibodies against Capripoxvirus.Microbiology spectrum · 2025Article
- Progress in diagnostic methods and vaccines for lumpy skin disease virus: a path towards understanding the disease.Veterinary research communications · 2025Review
- Lumpy skin disease: A growing threat to the global livestock industry.Open veterinary journal · 2025Review
- Molecular characterization and phylogenetic analysis of the lumpy skin disease virus isolated in Al-Zawiya, Western Libya.Open veterinary journal · 2025Article
- Article
- The Current Epizootiological Situation of Three Major Viral Infections Affecting Cattle in Egypt.Viruses · 2024Review
- Article
- Prevalence of Lumpy Skin Disease in Africa: A Systematic Review and Meta-Analysis from 2007 to 2023.Veterinary medicine international · 2024Review
- An evaluation of financial losses due to lumpy skin disease outbreaks in dairy farms of northern Thailand.Frontiers in veterinary science · 2024Article
- Unveiling Oxidative Stress-Induced Genotoxicity and Its Alleviation through Selenium and Vitamin E Therapy in Naturally Infected Cattle with Lumpy Skin Disease.Veterinary sciences · 2023Article
- Review
- Emergency vaccination of cattle against lumpy skin disease: Evaluation of safety, efficacy, and potency of MEVACVeterinary research communications · 2023Article
- The Serological Response in Cattle following Administration of a Heterologous Sheep Pox Virus Strain Vaccine for Protection from Lumpy Skin Disease; Current Situation in Armenia.Veterinary sciences · 2023Article
- Article
- Article
- Tick-borne diseases in Egypt: A one health perspective.One health (Amsterdam, Netherlands) · 2022Review
- First detection and phylogenetic analysis of lumpy skin disease virus from Kinmen Island, Taiwan in 2020.The Journal of veterinary medical science · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The General Organization of the Veterinary Services in Egypt has adopted a sheeppox vaccination policy to control lumpy skin disease (LSD) in cattle. Over the course of the last two years, recurrent outbreaks were reported, with animals showing severe clinical signs and consequentially higher fatalities than that of cases reported in previous LSD outbreaks. A total of 1050 cattle showing typical clinical signs suggestive of LSD were clinically and pathologically investigated during 2017-2018. Skin nodules were collected and lumpy skin disease virus (LSDV) was screened in collected skin samples using PCR for the RPO-30 gene. Furthermore, the entire P32 protein coding gene was sequenced. Histopathology and immunohistochemistry of the skin nodules were also conducted. The obtained results showed an overall mortality rate of 6.86%. LSDV was confirmed in all the examined nodules as evidenced by immunohistochemistry and positive PCR amplification of the RPO30 gene. Sequencing analysis of the P32 gene revealed a highly conserved nature and genetic stability of the LSDV. The results of the present study show that the current vaccination protocol was not effective for a multitude of reasons. These results also serve as evidence for a strong recommendation of an amendment of homologous vaccine use aside from a complete coverage of cattle populations in order to reduce the incidence of LSD among cattle population in Egypt.
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