ArticleScience advances2021
Plant cell adhesion and growth on artificial fibrous scaffolds as an in vitro model for plant development.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Modular noncovalent functionalization of electrospun piezoelectric scaffolds with bioactive nanocarriers.Biomaterials science · 2026Article
- Controlled delivery of phosphate to plants with optimized chemical and physical factors.Quantitative plant biology · 2025Article
- A sandwiched patch toward leakage-free and anti-postoperative tissue adhesion sealing of intestinal injuries.Bioactive materials · 2023Article
- Polygalacturonase activity promotes aberrant cell separation in theCell surface (Amsterdam, Netherlands) · 2022Article
- Characterising the mechanics of cell-cell adhesion in plants.Quantitative plant biology · 2022Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanistic studies of plant development would benefit from an in vitro model that mimics the endogenous physical interactions between cells and their microenvironment. Here, we present artificial scaffolds to which both solid- and liquid-cultured tobacco BY-2 cells adhere without perturbing cell morphology, division, and cortical microtubule organization. Scaffolds consisting of polyvinylidene tri-fluoroethylene (PVDF-TrFE) were prepared to mimic the cell wall’s fibrillar structure and its relative hydrophobicity and piezoelectric property. We found that cells adhered best to scaffolds consisting of nanosized aligned fibers. In addition, poling of PVDF-TrFE, which orients the fiber dipoles and renders the scaffold more piezoelectric, increased cell adhesion. Enzymatic treatments revealed that the plant cell wall polysaccharide, pectin, is largely responsible for cell adhesion to scaffolds, analogous to pectin-mediated cell adhesion in plant tissues. Together, this work establishes the first plant biomimetic scaffolds that will enable studies of how cell-cell and cell-matrix interactions affect plant developmental pathways.
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Registered trials
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